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- W2000885178 abstract "This article reviews criteria for the histopathologic diagnosis of benign and malignant fibrous and fibrohistiocytic proliferations of the skin. These lesions are composed of several of the following elements in variable proportions: fibroblasts, myofibroblasts, histiocytes, dermal dendrocytes, collagen, elastic fibers, and connective tissue mucin.5, 9, 32, 47 The benign proliferations are very common tumors, and most of them are easily diagnosed on routine hematoxylin-and-eosin– stained sections. There are variants of these lesions that show cytologic atypia or unusual features that could be mistaken for malignant neoplasms. Histopathologic criteria and immunohistochemical reactions that are helpful in distinguishing among these entities are listed in this article. Immunohistochemistry for vimentin, CD34, muscle-specific actin, factor XIIIa, and histiocytic markers KP-1, HAM 56, and α1–antichymotrypsin are very helpful in distinguishing among these entities, but there are some pitfalls in their interpretation. This is an expanded update of an article that appeared in Dermatologic Clinics in 1992." @default.
- W2000885178 created "2016-06-24" @default.
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- W2000885178 date "1999-07-01" @default.
- W2000885178 modified "2023-10-01" @default.
- W2000885178 title "HISTOPATHOLOGIC AND IMMUNOHISTOCHEMICAL DIAGNOSIS OF BENIGN AND MALIGNANT FIBROUS AND FIBROHISTIOCYTIC TUMORS OF THE SKIN" @default.
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- W2000885178 doi "https://doi.org/10.1016/s0733-8635(05)70103-0" @default.
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