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- W2000887487 abstract "Mucormycosis or zygomycosis is a group of infections caused by filamentous fungi of the mucorales order belonging to the zygomycetes family. They generally appear in patients with uncontrolled diabetes or immunodepression, especially neutropenic immunodepression. Incidence has increased with progress in immunosuppressive therapy and chemotherapy and the absence of the use of antifungal prophylactic agents effective against mucors.We report the case of a diabetic patient presenting with an excavated opacity in the right lung which failed to improve after receiving non-specific antibiotic treatment. Direct examination of the bronchial washing specimen led to the diagnosis of pulmonary mucormycosis. Prognosis depends mainly on early diagnosis, enabling appropriate treatment with amphotericin B. Mortality remains high, around 80%; diagnosis is commonly established post-mortem.Les mucormycoses ou zygormycoses représentent un groupe d’infections causées par des champignons filamenteux de l’ordre des mucorales appartenant à la famille des zygomycètes. Elles se développent généralement chez les patients diabétiques mal équilibrés et les immunodéprimés, essentiellement les neutropéniques. Leur incidence est en augmentation compte-tenu d’une part des progrès des thérapeutiques immunosuppressives et de la chimiothérapie et d’autre part de l’absence d’utilisation de prophylaxie antifungique couvrant les mucors. Nous rapportons dans l’observation suivante le cas d’un patient diabétique qui a été suivi pour une opacité pulmonaire droite excavée et traité par une antibiothérapie non spécifique sans amélioration. Le diagnostic de mucormycose pulmonaire a été retenu par l’examen direct du liquide de lavage bronchique. L’élément déterminant du pronostic est la précocité du diagnostic afin de démarrer un traitement immédiat basé sur l’amphotéricine B. La mortalité reste élevée aux alentours de 80 % et le diagnostic est fréquemment tardif, en post-mortem." @default.
- W2000887487 created "2016-06-24" @default.
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- W2000887487 date "2010-09-01" @default.
- W2000887487 modified "2023-09-26" @default.
- W2000887487 title "Une opacité pulmonaire chez un sujet âgé" @default.
- W2000887487 doi "https://doi.org/10.1016/s1261-694x(10)70109-7" @default.
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