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- W2000888109 abstract "Normal resting muscle exhibits at the end plate constantly recurring miniature potentials attributable to the release from motor-nerve endings of subliminal quanta of acetylcholine, which diffuses across the synaptic cleft and binds to receptors in the subsynaptic membrane. This action increases ionic permeability of the membrane, and the movement of sodium ions into the muscle results in disappearance of the resting potential difference across the membrane (depolarization), localized to the end-plate region. When a nerve impulse reaches the motor-nerve endings, an enormously larger number of quanta of acetylcholine are released, depolarizing enough of the membrane to initiate a muscle action . . ." @default.
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- W2000888109 date "1976-03-25" @default.
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- W2000888109 title "Cause of Weakness in Myasthenia Gravis" @default.
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- W2000888109 doi "https://doi.org/10.1056/nejm197603252941312" @default.
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