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- W2000889524 abstract "We examined short-term outcomes and posttransplant medical complications under three different immunosuppressive regimens at a single center. The study design was a randomized, prospective, open-label trial comparing a calcineurin inhibitor-free (CNI) protocol to standard triple therapy with tacrolimus, prednisone, and mycophenolate mofetil. They were also compared to a concurrent but nonrandomized third cohort treated with a prednisone-free protocol. All three groups had excellent early outcomes with no significant difference in patient or graft survival or biopsy-proven acute rejection. Serum creatinine was significantly lower in the CNI-free recipients. Lipid panels and posttransplant diabetes mellitus were significantly lower in the prednisone-free patients. Prednisone-free kidney transplant recipients have improved early glucose metabolism and hyperlipidemia compared to CNI-free or standard triple therapy recipients with comparable rejection and graft survival rates." @default.
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- W2000889524 date "2006-12-01" @default.
- W2000889524 modified "2023-10-09" @default.
- W2000889524 title "Short-term Results Under Three Different Immunosuppressive Regimens at One Center" @default.
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- W2000889524 doi "https://doi.org/10.1016/j.transproceed.2006.10.098" @default.
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