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- W2000889791 abstract "Cloning of the mammalian basic transcription factors serves as a major step in understanding the mechanism of transcription initiation. The 62-kilodalton component (p62) of one of these transcription factors, BTF2 was cloned and overexpressed. A monoclonal antibody to this polypeptide inhibited transcription in vitro. Immunoaffinity experiments demonstrated that the 62-kilodalton component is closely associated with the other polypeptides present in the BTF2 factor. Sequence similarity suggests that BTF2 may be the human counterpart of RNA polymerase II initiation factor b from yeast." @default.
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- W2000889791 date "1992-09-04" @default.
- W2000889791 modified "2023-09-23" @default.
- W2000889791 title "Cloning of the 62-Kilodalton Component of Basic Transcription Factor BTF2" @default.
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- W2000889791 doi "https://doi.org/10.1126/science.1529339" @default.
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