Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000889863> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2000889863 endingPage "3118" @default.
- W2000889863 startingPage "3113" @default.
- W2000889863 abstract "We studied the transmembrane potential and magnetic fields from electrical activity at the apex of the isolated rabbit heart experimentally using optical mapping and superconducting quantum interference device microscopy, and theoretically using monodomain and bidomain models. The cardiac apex has a complex spiral fiber architecture that plays an important role in the development and propagation of action currents during stimulation at the apex. This spiral fiber orientation contains both radial electric currents that contribute to the electrocardiogram and electrically silent circular currents that cannot be detected by the electrocardiogram but are detectable by their magnetic field, B(z). In our experiments, the transmembrane potential, V(m), was first measured optically and then B(z) was measured with a superconducting quantum interference device microscope. Based on a simple model of the spiral structure of the apex, V(m) was expected to exhibit circular wave front patterns and B(z) to reflect the circular component of the action currents. Although the circular V(m) wave fronts were detected, the B(z) maps were not as simple as expected. However, we observed a pattern consistent with a tilted axis for the apex spiral fiber geometry. We were able to simulate similar patterns in both a monodomain model of a tilted stack of rings of dipole current and a bidomain model of a tilted stack of spiraled cardiac tissue that was stimulated at the apex. The fact that the spatial pattern of the magnetic data was more complex than the simple circles observed for V(m) suggests that the magnetic data contain information that cannot be found electrically." @default.
- W2000889863 created "2016-06-24" @default.
- W2000889863 creator A5003506688 @default.
- W2000889863 creator A5025539943 @default.
- W2000889863 creator A5027957010 @default.
- W2000889863 creator A5029305754 @default.
- W2000889863 creator A5077923587 @default.
- W2000889863 date "2010-11-01" @default.
- W2000889863 modified "2023-09-27" @default.
- W2000889863 title "Measurements of Transmembrane Potential and Magnetic Field at the Apex of the Heart" @default.
- W2000889863 cites W1515192127 @default.
- W2000889863 cites W1972111404 @default.
- W2000889863 cites W1973309256 @default.
- W2000889863 cites W1976206882 @default.
- W2000889863 cites W1976341739 @default.
- W2000889863 cites W1984336411 @default.
- W2000889863 cites W1987529970 @default.
- W2000889863 cites W1992154518 @default.
- W2000889863 cites W2039173298 @default.
- W2000889863 cites W2058364433 @default.
- W2000889863 cites W2063614586 @default.
- W2000889863 cites W2072967318 @default.
- W2000889863 cites W2105525130 @default.
- W2000889863 cites W2124346667 @default.
- W2000889863 cites W2133880202 @default.
- W2000889863 cites W2161395551 @default.
- W2000889863 cites W2161777515 @default.
- W2000889863 doi "https://doi.org/10.1016/j.bpj.2010.08.040" @default.
- W2000889863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2980705" @default.
- W2000889863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21081057" @default.
- W2000889863 hasPublicationYear "2010" @default.
- W2000889863 type Work @default.
- W2000889863 sameAs 2000889863 @default.
- W2000889863 citedByCount "10" @default.
- W2000889863 countsByYear W20008898632012 @default.
- W2000889863 countsByYear W20008898632014 @default.
- W2000889863 countsByYear W20008898632017 @default.
- W2000889863 countsByYear W20008898632020 @default.
- W2000889863 countsByYear W20008898632021 @default.
- W2000889863 countsByYear W20008898632023 @default.
- W2000889863 crossrefType "journal-article" @default.
- W2000889863 hasAuthorship W2000889863A5003506688 @default.
- W2000889863 hasAuthorship W2000889863A5025539943 @default.
- W2000889863 hasAuthorship W2000889863A5027957010 @default.
- W2000889863 hasAuthorship W2000889863A5029305754 @default.
- W2000889863 hasAuthorship W2000889863A5077923587 @default.
- W2000889863 hasBestOaLocation W20008898631 @default.
- W2000889863 hasConcept C115260700 @default.
- W2000889863 hasConcept C120665830 @default.
- W2000889863 hasConcept C121332964 @default.
- W2000889863 hasConcept C134306372 @default.
- W2000889863 hasConcept C173523689 @default.
- W2000889863 hasConcept C174128100 @default.
- W2000889863 hasConcept C192562407 @default.
- W2000889863 hasConcept C2524010 @default.
- W2000889863 hasConcept C26873012 @default.
- W2000889863 hasConcept C33923547 @default.
- W2000889863 hasConcept C62520636 @default.
- W2000889863 hasConcept C67139541 @default.
- W2000889863 hasConceptScore W2000889863C115260700 @default.
- W2000889863 hasConceptScore W2000889863C120665830 @default.
- W2000889863 hasConceptScore W2000889863C121332964 @default.
- W2000889863 hasConceptScore W2000889863C134306372 @default.
- W2000889863 hasConceptScore W2000889863C173523689 @default.
- W2000889863 hasConceptScore W2000889863C174128100 @default.
- W2000889863 hasConceptScore W2000889863C192562407 @default.
- W2000889863 hasConceptScore W2000889863C2524010 @default.
- W2000889863 hasConceptScore W2000889863C26873012 @default.
- W2000889863 hasConceptScore W2000889863C33923547 @default.
- W2000889863 hasConceptScore W2000889863C62520636 @default.
- W2000889863 hasConceptScore W2000889863C67139541 @default.
- W2000889863 hasIssue "10" @default.
- W2000889863 hasLocation W20008898631 @default.
- W2000889863 hasLocation W20008898632 @default.
- W2000889863 hasLocation W20008898633 @default.
- W2000889863 hasLocation W20008898634 @default.
- W2000889863 hasOpenAccess W2000889863 @default.
- W2000889863 hasPrimaryLocation W20008898631 @default.
- W2000889863 hasRelatedWork W1987643521 @default.
- W2000889863 hasRelatedWork W1998992221 @default.
- W2000889863 hasRelatedWork W2038105159 @default.
- W2000889863 hasRelatedWork W2082433475 @default.
- W2000889863 hasRelatedWork W2087765901 @default.
- W2000889863 hasRelatedWork W2329949735 @default.
- W2000889863 hasRelatedWork W2989442442 @default.
- W2000889863 hasRelatedWork W3086969599 @default.
- W2000889863 hasRelatedWork W3105723266 @default.
- W2000889863 hasRelatedWork W3106421699 @default.
- W2000889863 hasVolume "99" @default.
- W2000889863 isParatext "false" @default.
- W2000889863 isRetracted "false" @default.
- W2000889863 magId "2000889863" @default.
- W2000889863 workType "article" @default.