FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000890192> ?p ?o ?g. }

• W2000890192 endingPage "341" @default.
• W2000890192 startingPage "332" @default.
• W2000890192 abstract "The mechanisms by which atypical antipsychotic drugs such as clozapine exert therapeutic effects but do not induce extrapyramidal side effects are not clear. We have examined the effects of acute administration of three antipsychotic drugs on Fos protein expression in the striatal complex. The ypical neuroleptic haloperidol was compared with the atypical agent clozapine and the putative atypical antipsychotic drug remoxipride. Haloperidol increased the number of neurons expressing Fos-like immunoreactivity in both the dorsolateral and the medial striatum and increased Fos expression in the nucleus accumbens core and shell. Clozapine increased Fos in the nucleus accumbens shell, but not in the core or two neostriatal sectors. Remoxipride significantly increased the number of Fos-like immunoreactive neurons in the medial but not the dorsolateral striatum, and increased the number of cells expressing Fos protein in the nucleus accumbens shell but not core. The remoxipride-induced increase in the number of medial striatal neurons expressing Fos was entirely attributable to a selective increase in the striatal patch compartment, whereas haloperidol increased Fos protein in neurons of both striatal compartments. These data indicate that typical and atypical antipsychotic drugs exert regionally distinct effects on striatal Fos expression, and suggest that the dorsolateral striatum may be a locus involved in the genesis of extrapyramidal side effects. All three antipsychotic drugs increased Fos expression in the shell of the nucleus accumbens. The shell of the nucleus accumbens may be a site of antipsychotic action." @default.
• W2000890192 created "2016-06-24" @default.
• W2000890192 creator A5004080081 @default.
• W2000890192 creator A5006333981 @default.
• W2000890192 creator A5035428304 @default.
• W2000890192 date "1992-08-01" @default.
• W2000890192 modified "2023-10-17" @default.
• W2000890192 title "Regionally specific effects of atypical antipsychotic drugs on striatal Fos expression: The nucleus accumbens shell as a locus of antipsychotic action" @default.
• W2000890192 cites W1483520655 @default.
• W2000890192 cites W1503660373 @default.
• W2000890192 cites W1630214027 @default.
• W2000890192 cites W1664611502 @default.
• W2000890192 cites W1910298002 @default.
• W2000890192 cites W1966092598 @default.
• W2000890192 cites W1971695590 @default.
• W2000890192 cites W1971959365 @default.
• W2000890192 cites W1975193242 @default.
• W2000890192 cites W1978850926 @default.
• W2000890192 cites W1978885695 @default.
• W2000890192 cites W1985001303 @default.
• W2000890192 cites W1993855542 @default.
• W2000890192 cites W1997635941 @default.
• W2000890192 cites W2000073413 @default.
• W2000890192 cites W2001311556 @default.
• W2000890192 cites W2005487930 @default.
• W2000890192 cites W2007031350 @default.
• W2000890192 cites W2010110267 @default.
• W2000890192 cites W2010700904 @default.
• W2000890192 cites W2019115177 @default.
• W2000890192 cites W2022824713 @default.
• W2000890192 cites W2026835867 @default.
• W2000890192 cites W2027675670 @default.
• W2000890192 cites W2028404159 @default.
• W2000890192 cites W2030001934 @default.
• W2000890192 cites W2032551004 @default.
• W2000890192 cites W2033894560 @default.
• W2000890192 cites W2036424706 @default.
• W2000890192 cites W2037104097 @default.
• W2000890192 cites W2040844884 @default.
• W2000890192 cites W2042458199 @default.
• W2000890192 cites W2045412127 @default.
• W2000890192 cites W2046041603 @default.
• W2000890192 cites W2050760271 @default.
• W2000890192 cites W2051001886 @default.
• W2000890192 cites W2052294852 @default.
• W2000890192 cites W2053496450 @default.
• W2000890192 cites W2056445339 @default.
• W2000890192 cites W2057776879 @default.
• W2000890192 cites W2058037429 @default.
• W2000890192 cites W2058601367 @default.
• W2000890192 cites W2059230444 @default.
• W2000890192 cites W2059433193 @default.
• W2000890192 cites W2062134604 @default.
• W2000890192 cites W2062147570 @default.
• W2000890192 cites W2062610641 @default.
• W2000890192 cites W2066494910 @default.
• W2000890192 cites W2067388503 @default.
• W2000890192 cites W2067678628 @default.
• W2000890192 cites W2068026066 @default.
• W2000890192 cites W2069950515 @default.
• W2000890192 cites W2073595900 @default.
• W2000890192 cites W2073711860 @default.
• W2000890192 cites W2076170995 @default.
• W2000890192 cites W2078122061 @default.
• W2000890192 cites W2085360366 @default.
• W2000890192 cites W2086775652 @default.
• W2000890192 cites W2088415801 @default.
• W2000890192 cites W2112760226 @default.
• W2000890192 cites W2115736681 @default.
• W2000890192 cites W2119725374 @default.
• W2000890192 cites W2129429719 @default.
• W2000890192 cites W2141740560 @default.
• W2000890192 cites W2164298318 @default.
• W2000890192 cites W4232285896 @default.
• W2000890192 cites W4232623657 @default.
• W2000890192 doi "https://doi.org/10.1016/1044-7431(92)90030-6" @default.
• W2000890192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19912876" @default.
• W2000890192 hasPublicationYear "1992" @default.
• W2000890192 type Work @default.
• W2000890192 sameAs 2000890192 @default.
• W2000890192 citedByCount "228" @default.
• W2000890192 countsByYear W20008901922012 @default.
• W2000890192 countsByYear W20008901922013 @default.
• W2000890192 countsByYear W20008901922014 @default.
• W2000890192 countsByYear W20008901922015 @default.
• W2000890192 countsByYear W20008901922016 @default.
• W2000890192 countsByYear W20008901922017 @default.
• W2000890192 countsByYear W20008901922018 @default.
• W2000890192 countsByYear W20008901922019 @default.
• W2000890192 countsByYear W20008901922020 @default.
• W2000890192 countsByYear W20008901922021 @default.
• W2000890192 countsByYear W20008901922022 @default.
• W2000890192 crossrefType "journal-article" @default.
• W2000890192 hasAuthorship W2000890192A5004080081 @default.
• W2000890192 hasAuthorship W2000890192A5006333981 @default.
• W2000890192 hasAuthorship W2000890192A5035428304 @default.
• W2000890192 hasConcept C118552586 @default.
• W2000890192 hasConcept C15744967 @default.

• next