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- W2000892733 abstract "In the past essential thrombocythemia was considered a disease of the elderly. At present, the number of young people suffering from this disease is growing, with a slightly higher frequency in females. We investigated the effects of interferon alfa therapy in these patients.We describe 9 pregnancies in 4 women affected by essential thrombocythemia.Four pregnancies were carried out without interferon alfa therapy, and resulted in 2 intrauterine deaths, 1 spontaneous abortion, and 1 neonatal death. Interferon alfa was given during another 5 pregnancies; among them, 2 ended in preterm deliveries with normal infants, and 3 in full-term deliveries. The literature is reviewed.Our cases and published series suggest that fetal outcome is improved by therapy, and that interferon alfa may be the best therapeutic option." @default.
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- W2000892733 date "2004-12-01" @default.
- W2000892733 modified "2023-09-24" @default.
- W2000892733 title "Interferon alfa treatment for pregnant women affected by essential thrombocythemia: Case reports and a review" @default.
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- W2000892733 doi "https://doi.org/10.1016/j.ajog.2004.05.001" @default.
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