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- W2000894710 abstract "Abstract A simple, sensitive, reversed-phase liquid chromatographic assay is reported for the simultaneous determination of disulfiram, diethyldithiocarbamate (DDC) and its methyl ester (MeDDC) in human plasma. A single-step extractive ethylation converts DDC to its ethyl ester which is then separated from endogenously produced MeDDC and parent disulfiram on an alkylphenyl column. The method is sufficiently sensitive (25 ng/ml) to permit DDC and MeDDC determination in patients receiving therapeutic doses of disulfiram." @default.
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- W2000894710 date "1981-08-01" @default.
- W2000894710 modified "2023-09-27" @default.
- W2000894710 title "Simultaneous determination of disulfiram and two of its dithiocarbamate metabolites in human plasma by reversed-phase liquid chromatography" @default.
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- W2000894710 doi "https://doi.org/10.1016/s0378-4347(00)80219-4" @default.
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