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- W2000895159 abstract "Indoleamine 2,3-dioxygenase (IDO)-initiated tryptophan (Trp) metabolism along the kynurenine (Kyn) pathway regulates T cell responses. However, it is not clear whether bone marrow-derived myeloid dendritic cells (BMDC) express functional IDO. In this study, BMDC expressed IDO protein with nitric oxide (NO) production by CpG oligodeoxynucleotides (CpG), and the CpG-mediated induction of IDO activity in BMDC was severely down-regulated by NO. The error in the estimation of Kyn assay was induced by the reaction of Kyn with nitrite under acidic conditions." @default.
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- W2000895159 date "2007-11-01" @default.
- W2000895159 modified "2023-09-23" @default.
- W2000895159 title "Trichloroacetic acid-triggered reaction of kynurenine with nitrite produced by bone marrow-derived myeloid dendritic cells stimulated with CpG" @default.
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- W2000895159 doi "https://doi.org/10.1016/j.ics.2007.07.027" @default.
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