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- W2000900918 abstract "A method is described which permits to determine in vivo and in a short period of time (4-6 hours) the sensitivity of T. cruzi strains to known active chemotherapeutic agents. By using resistant- and sensitive T. cruzi strains a fairly good correlation was observed between the results obtained with this rapid method (which detects activity against the circulating blood forms) and those obtained with long-term schedules which involve drug administration for at least 20 consecutive days and a prolonged period of assessment. This method may be used to characterize susceptibility to active drugs used clinically, provide information on the specific action against circulating trypomastigotes and screen active compounds." @default.
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- W2000900918 date "1984-06-01" @default.
- W2000900918 modified "2023-10-14" @default.
- W2000900918 title "A rapid method for testing in vivo the susceptibility of different strains of Trypanosoma cruzi to active chemotherapeutic agents" @default.
- W2000900918 doi "https://doi.org/10.1590/s0074-02761984000200008" @default.
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