Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000903926> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2000903926 endingPage "3669" @default.
- W2000903926 startingPage "3668" @default.
- W2000903926 abstract "RNA oxidation is important in the etiology of disease and as a tool for studying the structure and folding kinetics of this biopolymer. Nucleobase radicals are the major family of reactive intermediates produced in RNA exposed to diffusible species such as hydroxyl radical. The nucleobase radicals are believed to produce direct strand breaks by abstracting hydrogen atoms from their own and neighboring ribose rings. By independently generating the formal C5 hydrogen atom addition product of uridine in RNA, we provide the first chemical characterization of the pathway for direct strand scission from an RNA nucleobase radical. The process is more efficient under anaerobic conditions. The preference for strand scission in double-stranded RNA over single-stranded RNA suggests that this chemistry may be useful for analyzing the secondary structure of RNA in hydroxyl radical cleavage experiments if they are carried out under anaerobic conditions." @default.
- W2000903926 created "2016-06-24" @default.
- W2000903926 creator A5074662951 @default.
- W2000903926 creator A5079592298 @default.
- W2000903926 creator A5087642554 @default.
- W2000903926 date "2010-02-25" @default.
- W2000903926 modified "2023-09-27" @default.
- W2000903926 title "Direct Strand Scission from a Nucleobase Radical in RNA" @default.
- W2000903926 cites W1977637931 @default.
- W2000903926 cites W1978161934 @default.
- W2000903926 cites W1981541585 @default.
- W2000903926 cites W1986581714 @default.
- W2000903926 cites W1990320656 @default.
- W2000903926 cites W2015193441 @default.
- W2000903926 cites W2028553114 @default.
- W2000903926 cites W2028976892 @default.
- W2000903926 cites W2036690044 @default.
- W2000903926 cites W2041985732 @default.
- W2000903926 cites W2050844955 @default.
- W2000903926 cites W2055593010 @default.
- W2000903926 cites W2083778092 @default.
- W2000903926 cites W2160568246 @default.
- W2000903926 cites W2339669481 @default.
- W2000903926 doi "https://doi.org/10.1021/ja100281x" @default.
- W2000903926 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2845440" @default.
- W2000903926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20184313" @default.
- W2000903926 hasPublicationYear "2010" @default.
- W2000903926 type Work @default.
- W2000903926 sameAs 2000903926 @default.
- W2000903926 citedByCount "51" @default.
- W2000903926 countsByYear W20009039262012 @default.
- W2000903926 countsByYear W20009039262013 @default.
- W2000903926 countsByYear W20009039262014 @default.
- W2000903926 countsByYear W20009039262015 @default.
- W2000903926 countsByYear W20009039262016 @default.
- W2000903926 countsByYear W20009039262017 @default.
- W2000903926 countsByYear W20009039262018 @default.
- W2000903926 countsByYear W20009039262019 @default.
- W2000903926 countsByYear W20009039262020 @default.
- W2000903926 countsByYear W20009039262021 @default.
- W2000903926 countsByYear W20009039262022 @default.
- W2000903926 crossrefType "journal-article" @default.
- W2000903926 hasAuthorship W2000903926A5074662951 @default.
- W2000903926 hasAuthorship W2000903926A5079592298 @default.
- W2000903926 hasAuthorship W2000903926A5087642554 @default.
- W2000903926 hasBestOaLocation W20009039262 @default.
- W2000903926 hasConcept C104317684 @default.
- W2000903926 hasConcept C139066938 @default.
- W2000903926 hasConcept C161790260 @default.
- W2000903926 hasConcept C185592680 @default.
- W2000903926 hasConcept C3044715 @default.
- W2000903926 hasConcept C552990157 @default.
- W2000903926 hasConcept C55493867 @default.
- W2000903926 hasConcept C61234307 @default.
- W2000903926 hasConcept C67705224 @default.
- W2000903926 hasConcept C71240020 @default.
- W2000903926 hasConceptScore W2000903926C104317684 @default.
- W2000903926 hasConceptScore W2000903926C139066938 @default.
- W2000903926 hasConceptScore W2000903926C161790260 @default.
- W2000903926 hasConceptScore W2000903926C185592680 @default.
- W2000903926 hasConceptScore W2000903926C3044715 @default.
- W2000903926 hasConceptScore W2000903926C552990157 @default.
- W2000903926 hasConceptScore W2000903926C55493867 @default.
- W2000903926 hasConceptScore W2000903926C61234307 @default.
- W2000903926 hasConceptScore W2000903926C67705224 @default.
- W2000903926 hasConceptScore W2000903926C71240020 @default.
- W2000903926 hasIssue "11" @default.
- W2000903926 hasLocation W20009039261 @default.
- W2000903926 hasLocation W20009039262 @default.
- W2000903926 hasLocation W20009039263 @default.
- W2000903926 hasLocation W20009039264 @default.
- W2000903926 hasOpenAccess W2000903926 @default.
- W2000903926 hasPrimaryLocation W20009039261 @default.
- W2000903926 hasRelatedWork W1596618156 @default.
- W2000903926 hasRelatedWork W1991770485 @default.
- W2000903926 hasRelatedWork W2000903926 @default.
- W2000903926 hasRelatedWork W2069075036 @default.
- W2000903926 hasRelatedWork W2099590466 @default.
- W2000903926 hasRelatedWork W2801988987 @default.
- W2000903926 hasRelatedWork W2884547178 @default.
- W2000903926 hasRelatedWork W2898614381 @default.
- W2000903926 hasRelatedWork W3160381330 @default.
- W2000903926 hasRelatedWork W1993202971 @default.
- W2000903926 hasVolume "132" @default.
- W2000903926 isParatext "false" @default.
- W2000903926 isRetracted "false" @default.
- W2000903926 magId "2000903926" @default.
- W2000903926 workType "article" @default.