FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000906336> ?p ?o ?g. }

• W2000906336 endingPage "454" @default.
• W2000906336 startingPage "450" @default.
• W2000906336 abstract "Vascular endothelial growth factor (VEGF₁₆₅) is stored, transported and released by platelets. Platelet functional abnormalities have been described in patients with hepatocellular carcinoma (HCC). Thus, this study was designed to investigate the behavior of VEGF₁₆₅ with respect to platelet activation in HCC.Plasma and serum VEGF₁₆₅ and plasma sP-selectin levels were analyzed in patients with HCC (n=70) or cirrhosis (n=45) and control subjects (n=70). Given the thrombocytopenia that characterizes both HCC and cirrhotic patients, plasma VEGF₁₆₅ and sP-selectin as well as serum VEGF (plt-VEGF₁₆₅-load) levels were normalized by platelet counts.Median concentrations of plasma VEGF₁₆₅/platelet (p=0.002) and sP-selectin/platelet (p<0.0001) were higher in HCC or cirrhotic patients compared to controls. Moreover, sP-selectin/platelet was the only independent variable predictive of plasma VEGF₁₆₅/platelet at multivariate analysis (p<0.0001). Conversely, plt-VEGF₁₆₅-load correlated with tumor diameter (p<0.05) but not with sP-selectin/platelet and was an independent predictor for 5year overall survival (p=0.012).The results obtained are suggestive for VEGF₁₆₅ release by tumor in HCC. It is plt-VEGF₁₆₅-load, but not plasma VEGF₁₆₅ or serum VEGF₁₆₅ that is an independent predictor for overall survival of HCC patients." @default.
• W2000906336 created "2016-06-24" @default.
• W2000906336 creator A5001775307 @default.
• W2000906336 creator A5015785063 @default.
• W2000906336 creator A5027544987 @default.
• W2000906336 creator A5030351372 @default.
• W2000906336 creator A5044218937 @default.
• W2000906336 creator A5049148280 @default.
• W2000906336 creator A5053483781 @default.
• W2000906336 creator A5067043896 @default.
• W2000906336 creator A5067110273 @default.
• W2000906336 creator A5087184743 @default.
• W2000906336 date "2011-02-01" @default.
• W2000906336 modified "2023-09-27" @default.
• W2000906336 title "Platelet activation and vascular endothelial growth factor 165 release in hepatocellular cancer" @default.
• W2000906336 cites W1573207765 @default.
• W2000906336 cites W1573363574 @default.
• W2000906336 cites W1901908573 @default.
• W2000906336 cites W1965779501 @default.
• W2000906336 cites W2003656890 @default.
• W2000906336 cites W2019832083 @default.
• W2000906336 cites W2033686248 @default.
• W2000906336 cites W2047679549 @default.
• W2000906336 cites W2134648032 @default.
• W2000906336 cites W2143079361 @default.
• W2000906336 cites W2158696324 @default.
• W2000906336 cites W2314748577 @default.
• W2000906336 cites W2321119966 @default.
• W2000906336 cites W2399196955 @default.
• W2000906336 cites W2407594696 @default.
• W2000906336 cites W2431827525 @default.
• W2000906336 cites W4237373900 @default.
• W2000906336 doi "https://doi.org/10.1016/j.cca.2010.11.026" @default.
• W2000906336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21111726" @default.
• W2000906336 hasPublicationYear "2011" @default.
• W2000906336 type Work @default.
• W2000906336 sameAs 2000906336 @default.
• W2000906336 citedByCount "16" @default.
• W2000906336 countsByYear W20009063362013 @default.
• W2000906336 countsByYear W20009063362014 @default.
• W2000906336 countsByYear W20009063362015 @default.
• W2000906336 countsByYear W20009063362017 @default.
• W2000906336 countsByYear W20009063362018 @default.
• W2000906336 countsByYear W20009063362019 @default.
• W2000906336 countsByYear W20009063362022 @default.
• W2000906336 countsByYear W20009063362023 @default.
• W2000906336 crossrefType "journal-article" @default.
• W2000906336 hasAuthorship W2000906336A5001775307 @default.
• W2000906336 hasAuthorship W2000906336A5015785063 @default.
• W2000906336 hasAuthorship W2000906336A5027544987 @default.
• W2000906336 hasAuthorship W2000906336A5030351372 @default.
• W2000906336 hasAuthorship W2000906336A5044218937 @default.
• W2000906336 hasAuthorship W2000906336A5049148280 @default.
• W2000906336 hasAuthorship W2000906336A5053483781 @default.
• W2000906336 hasAuthorship W2000906336A5067043896 @default.
• W2000906336 hasAuthorship W2000906336A5067110273 @default.
• W2000906336 hasAuthorship W2000906336A5087184743 @default.
• W2000906336 hasConcept C126322002 @default.
• W2000906336 hasConcept C134018914 @default.
• W2000906336 hasConcept C167734588 @default.
• W2000906336 hasConcept C2777025900 @default.
• W2000906336 hasConcept C2777214474 @default.
• W2000906336 hasConcept C2778019345 @default.
• W2000906336 hasConcept C3018697912 @default.
• W2000906336 hasConcept C56701166 @default.
• W2000906336 hasConcept C71924100 @default.
• W2000906336 hasConcept C89560881 @default.
• W2000906336 hasConcept C90924648 @default.
• W2000906336 hasConceptScore W2000906336C126322002 @default.
• W2000906336 hasConceptScore W2000906336C134018914 @default.
• W2000906336 hasConceptScore W2000906336C167734588 @default.
• W2000906336 hasConceptScore W2000906336C2777025900 @default.
• W2000906336 hasConceptScore W2000906336C2777214474 @default.
• W2000906336 hasConceptScore W2000906336C2778019345 @default.
• W2000906336 hasConceptScore W2000906336C3018697912 @default.
• W2000906336 hasConceptScore W2000906336C56701166 @default.
• W2000906336 hasConceptScore W2000906336C71924100 @default.
• W2000906336 hasConceptScore W2000906336C89560881 @default.
• W2000906336 hasConceptScore W2000906336C90924648 @default.
• W2000906336 hasIssue "5-6" @default.
• W2000906336 hasLocation W20009063361 @default.
• W2000906336 hasLocation W20009063362 @default.
• W2000906336 hasOpenAccess W2000906336 @default.
• W2000906336 hasPrimaryLocation W20009063361 @default.
• W2000906336 hasRelatedWork W1989244033 @default.
• W2000906336 hasRelatedWork W1995827984 @default.
• W2000906336 hasRelatedWork W2266860383 @default.
• W2000906336 hasRelatedWork W2375267808 @default.
• W2000906336 hasRelatedWork W2396486584 @default.
• W2000906336 hasRelatedWork W2511910244 @default.
• W2000906336 hasRelatedWork W3030449887 @default.
• W2000906336 hasRelatedWork W3032094436 @default.
• W2000906336 hasRelatedWork W325818975 @default.
• W2000906336 hasRelatedWork W2101010353 @default.
• W2000906336 hasVolume "412" @default.
• W2000906336 isParatext "false" @default.
• W2000906336 isRetracted "false" @default.
• W2000906336 magId "2000906336" @default.

• next