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- W2000908943 endingPage "44" @default.
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- W2000908943 abstract "Introduction: Over the past decade, the introduction of a new class of anti-TNFα drugs has dramatically changed the approach taken to the management of Crohn’s disease (CD). An increasing number of patients are receiving treatment with these advanced biological therapies, and the risk of adverse events that may be associated with their use must be carefully evaluated.Areas covered: Safety data about the three anti-TNFα drugs currently approved for use in CD patients (infliximab, adalimumab, and certolizumab pegol) is critically evaluated, including data coming from randomized clinical trials and post-marketing reports. Possible side effects of anti-TNFα agents are presented as drug-, class- and disease-specific adverse events. Management strategies to minimize the occurrence of side effects are summarized.Expert opinion: The safety profile of the three anti-TNFα drugs approved for clinical use in CD patients appears to be comparable among drugs. Data from clinical trials and a growing body of information from post-marketing surveillance indicate that anti-TNFα agents are generally safe, and that most of the observed side effects are mild and easily manageable. Nonetheless, serious short- and long-term adverse events may occur. Accurate selection of patients, careful pre-treatment evaluation, and regular follow-up during therapy could potentially reduce the rate of adverse events related to the use of anti-TNFα drugs." @default.
- W2000908943 created "2016-06-24" @default.
- W2000908943 creator A5008150296 @default.
- W2000908943 creator A5033593060 @default.
- W2000908943 creator A5041513244 @default.
- W2000908943 date "2014-11-15" @default.
- W2000908943 modified "2023-10-14" @default.
- W2000908943 title "Safety considerations when using anti-TNFα therapy to treat Crohn’s disease" @default.
- W2000908943 cites W1546652561 @default.
- W2000908943 cites W1562235336 @default.
- W2000908943 cites W1583184559 @default.
- W2000908943 cites W1964785646 @default.
- W2000908943 cites W1966122948 @default.
- W2000908943 cites W1969388440 @default.
- W2000908943 cites W1969469563 @default.
- W2000908943 cites W1971119469 @default.
- W2000908943 cites W1971685694 @default.
- W2000908943 cites W1972811610 @default.
- W2000908943 cites W1973976214 @default.
- W2000908943 cites W1976546496 @default.
- W2000908943 cites W1984455842 @default.
- W2000908943 cites W1985627874 @default.
- W2000908943 cites W1986125265 @default.
- W2000908943 cites W1987469368 @default.
- W2000908943 cites W1988825081 @default.
- W2000908943 cites W1989167852 @default.
- W2000908943 cites W1991810959 @default.
- W2000908943 cites W1997999969 @default.
- W2000908943 cites W1999475844 @default.
- W2000908943 cites W1999767041 @default.
- W2000908943 cites W2000500639 @default.
- W2000908943 cites W2001681806 @default.
- W2000908943 cites W2002451630 @default.
- W2000908943 cites W2002780176 @default.
- W2000908943 cites W2003314961 @default.
- W2000908943 cites W2008497900 @default.
- W2000908943 cites W2010463972 @default.
- W2000908943 cites W2012526769 @default.
- W2000908943 cites W2017175280 @default.
- W2000908943 cites W2018933969 @default.
- W2000908943 cites W2021225630 @default.
- W2000908943 cites W2022150136 @default.
- W2000908943 cites W2023433479 @default.
- W2000908943 cites W2024162533 @default.
- W2000908943 cites W2024269361 @default.
- W2000908943 cites W2026116536 @default.
- W2000908943 cites W2028672514 @default.
- W2000908943 cites W2028935045 @default.
- W2000908943 cites W2034394392 @default.
- W2000908943 cites W2036202992 @default.
- W2000908943 cites W2038457542 @default.
- W2000908943 cites W2038535814 @default.
- W2000908943 cites W2039633848 @default.
- W2000908943 cites W2045789990 @default.
- W2000908943 cites W2051028531 @default.
- W2000908943 cites W2055176162 @default.
- W2000908943 cites W2056348171 @default.
- W2000908943 cites W2058321458 @default.
- W2000908943 cites W2064275071 @default.
- W2000908943 cites W2065791817 @default.
- W2000908943 cites W2071187468 @default.
- W2000908943 cites W2073537920 @default.
- W2000908943 cites W2075495244 @default.
- W2000908943 cites W2086050457 @default.
- W2000908943 cites W2087273286 @default.
- W2000908943 cites W2104015736 @default.
- W2000908943 cites W2105816635 @default.
- W2000908943 cites W2107174064 @default.
- W2000908943 cites W2107714591 @default.
- W2000908943 cites W2112635226 @default.
- W2000908943 cites W2115112939 @default.
- W2000908943 cites W2116048670 @default.
- W2000908943 cites W2118028203 @default.
- W2000908943 cites W2121609590 @default.
- W2000908943 cites W2126510103 @default.
- W2000908943 cites W2127693350 @default.
- W2000908943 cites W2128230250 @default.
- W2000908943 cites W2131882149 @default.
- W2000908943 cites W2131999276 @default.
- W2000908943 cites W2135423184 @default.
- W2000908943 cites W2137321809 @default.
- W2000908943 cites W2137775651 @default.
- W2000908943 cites W2138534069 @default.
- W2000908943 cites W2139369492 @default.
- W2000908943 cites W2141912213 @default.
- W2000908943 cites W2143221258 @default.
- W2000908943 cites W2146685023 @default.
- W2000908943 cites W2148497851 @default.
- W2000908943 cites W2152026434 @default.
- W2000908943 cites W2155922890 @default.
- W2000908943 cites W2159513257 @default.
- W2000908943 cites W2165107045 @default.
- W2000908943 cites W2166360124 @default.
- W2000908943 cites W2168370388 @default.
- W2000908943 cites W2171341132 @default.
- W2000908943 cites W2321453230 @default.
- W2000908943 cites W2326330820 @default.
- W2000908943 cites W2331617350 @default.