FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000912877> ?p ?o ?g. }

• W2000912877 endingPage "21460" @default.
• W2000912877 startingPage "21457" @default.
• W2000912877 abstract "Staphylococcus aureus expresses various surface proteins which specifically recognize and bind to different host molecules. We have previously identified a bacterial protein that exhibits a broad specificity and binds to several mammalian extracellular proteins. The gene encoding this bacterial component has now been cloned and sequenced. The deduced protein consists predominantly of six repeated domains of 110 residues. Each of the repeated domains contain a subdomain of 31 residues that share striking sequence homology with a segment in the peptide binding groove of the β chain of the major histocompatibility complex (MHC) class II proteins from different mammalian species. The purified recombinant bacterial protein bound several mammalian proteins, including recombinant osteopontin, suggesting a protein-protein interaction and also specifically recognized a 15-amino acid residue synthetic peptide. Taken together, these results suggest that the bacterial protein resembles mammalian MHC class II molecules with respect to both sequence similarities and peptide binding capabilities. Staphylococcus aureus expresses various surface proteins which specifically recognize and bind to different host molecules. We have previously identified a bacterial protein that exhibits a broad specificity and binds to several mammalian extracellular proteins. The gene encoding this bacterial component has now been cloned and sequenced. The deduced protein consists predominantly of six repeated domains of 110 residues. Each of the repeated domains contain a subdomain of 31 residues that share striking sequence homology with a segment in the peptide binding groove of the β chain of the major histocompatibility complex (MHC) class II proteins from different mammalian species. The purified recombinant bacterial protein bound several mammalian proteins, including recombinant osteopontin, suggesting a protein-protein interaction and also specifically recognized a 15-amino acid residue synthetic peptide. Taken together, these results suggest that the bacterial protein resembles mammalian MHC class II molecules with respect to both sequence similarities and peptide binding capabilities." @default.
• W2000912877 created "2016-06-24" @default.
• W2000912877 creator A5003966940 @default.
• W2000912877 creator A5005939116 @default.
• W2000912877 creator A5036477235 @default.
• W2000912877 creator A5062527254 @default.
• W2000912877 creator A5090570143 @default.
• W2000912877 date "1995-09-01" @default.
• W2000912877 modified "2023-10-18" @default.
• W2000912877 title "Staphylococcus aureus Expresses a Major Histocompatibility Complex Class II Analog" @default.
• W2000912877 cites W1601256941 @default.
• W2000912877 cites W1914841321 @default.
• W2000912877 cites W1993096337 @default.
• W2000912877 cites W1995134733 @default.
• W2000912877 cites W2010544851 @default.
• W2000912877 cites W2017526911 @default.
• W2000912877 cites W2022911712 @default.
• W2000912877 cites W2026397135 @default.
• W2000912877 cites W2043745393 @default.
• W2000912877 cites W2072527127 @default.
• W2000912877 cites W2074222872 @default.
• W2000912877 cites W2080956086 @default.
• W2000912877 cites W2101820543 @default.
• W2000912877 cites W2106481565 @default.
• W2000912877 cites W2137408395 @default.
• W2000912877 cites W2137869764 @default.
• W2000912877 cites W2139293110 @default.
• W2000912877 cites W2148564763 @default.
• W2000912877 cites W2176472482 @default.
• W2000912877 cites W274984332 @default.
• W2000912877 doi "https://doi.org/10.1074/jbc.270.37.21457" @default.
• W2000912877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7545162" @default.
• W2000912877 hasPublicationYear "1995" @default.
• W2000912877 type Work @default.
• W2000912877 sameAs 2000912877 @default.
• W2000912877 citedByCount "115" @default.
• W2000912877 countsByYear W20009128772012 @default.
• W2000912877 countsByYear W20009128772014 @default.
• W2000912877 countsByYear W20009128772015 @default.
• W2000912877 countsByYear W20009128772016 @default.
• W2000912877 countsByYear W20009128772017 @default.
• W2000912877 countsByYear W20009128772018 @default.
• W2000912877 countsByYear W20009128772019 @default.
• W2000912877 countsByYear W20009128772020 @default.
• W2000912877 countsByYear W20009128772023 @default.
• W2000912877 crossrefType "journal-article" @default.
• W2000912877 hasAuthorship W2000912877A5003966940 @default.
• W2000912877 hasAuthorship W2000912877A5005939116 @default.
• W2000912877 hasAuthorship W2000912877A5036477235 @default.
• W2000912877 hasAuthorship W2000912877A5062527254 @default.
• W2000912877 hasAuthorship W2000912877A5090570143 @default.
• W2000912877 hasBestOaLocation W20009128771 @default.
• W2000912877 hasConcept C104317684 @default.
• W2000912877 hasConcept C165525559 @default.
• W2000912877 hasConcept C167625842 @default.
• W2000912877 hasConcept C199216141 @default.
• W2000912877 hasConcept C207936829 @default.
• W2000912877 hasConcept C2779281246 @default.
• W2000912877 hasConcept C2779489039 @default.
• W2000912877 hasConcept C40767141 @default.
• W2000912877 hasConcept C523546767 @default.
• W2000912877 hasConcept C54355233 @default.
• W2000912877 hasConcept C55493867 @default.
• W2000912877 hasConcept C86803240 @default.
• W2000912877 hasConceptScore W2000912877C104317684 @default.
• W2000912877 hasConceptScore W2000912877C165525559 @default.
• W2000912877 hasConceptScore W2000912877C167625842 @default.
• W2000912877 hasConceptScore W2000912877C199216141 @default.
• W2000912877 hasConceptScore W2000912877C207936829 @default.
• W2000912877 hasConceptScore W2000912877C2779281246 @default.
• W2000912877 hasConceptScore W2000912877C2779489039 @default.
• W2000912877 hasConceptScore W2000912877C40767141 @default.
• W2000912877 hasConceptScore W2000912877C523546767 @default.
• W2000912877 hasConceptScore W2000912877C54355233 @default.
• W2000912877 hasConceptScore W2000912877C55493867 @default.
• W2000912877 hasConceptScore W2000912877C86803240 @default.
• W2000912877 hasIssue "37" @default.
• W2000912877 hasLocation W20009128771 @default.
• W2000912877 hasOpenAccess W2000912877 @default.
• W2000912877 hasPrimaryLocation W20009128771 @default.
• W2000912877 hasRelatedWork W2002335391 @default.
• W2000912877 hasRelatedWork W2017682998 @default.
• W2000912877 hasRelatedWork W2024084862 @default.
• W2000912877 hasRelatedWork W2028934005 @default.
• W2000912877 hasRelatedWork W2042601305 @default.
• W2000912877 hasRelatedWork W2050047627 @default.
• W2000912877 hasRelatedWork W2080634903 @default.
• W2000912877 hasRelatedWork W2370709181 @default.
• W2000912877 hasRelatedWork W2741822043 @default.
• W2000912877 hasRelatedWork W634089478 @default.
• W2000912877 hasVolume "270" @default.
• W2000912877 isParatext "false" @default.
• W2000912877 isRetracted "false" @default.
• W2000912877 magId "2000912877" @default.
• W2000912877 workType "article" @default.