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- W2000916819 abstract "In order to search for new chelating agents, widely employed methodologies in the chemistry of organophosphorus compounds such as the Michaelis-Arbuzov and Michaelis-Becker reactions were used to synthesize new bisphosphonates in high yields. The importance of the synthesis of these compounds resides in their potential capability of complexing different metals, all the more so because bisphosphonates have been widely employed in the diagnosis and therapy of several bone diseases, such as osteoporosis and hypercalcemia, as extracting agents for alkaline, alkaline earth, and transition metals, and also as reaction catalysts. All bisphosphonates synthesized were characterized by IR, 1 H-NMR, 13 C-NMR, 31 P-NMR, and mass spectroscopy." @default.
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- W2000916819 date "2002-01-01" @default.
- W2000916819 modified "2023-09-26" @default.
- W2000916819 title "Synthesis and Characterization of New Symmetrical Bisphosphonates" @default.
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- W2000916819 doi "https://doi.org/10.1080/10426500210231" @default.
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