FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000917485> ?p ?o ?g. }

• W2000917485 endingPage "1100" @default.
• W2000917485 startingPage "1093" @default.
• W2000917485 abstract "Cytoglobin (Cygb), a member of the hexacoordinate globin superfamily (hxHb), is expressed in fibroblasts from a broad range of tissues. The physiological functions of hxHb are still unclear, but biochemical studies reveal that they can scavenge toxic species, such as nitric oxide, peroxynitrite, and hydrogen peroxide. We demonstrate that the overexpression of Cygb in rat hepatic stellate cells, both in vitro and in vivo, protects against oxidative stress, inhibiting their differentiation into a myofibroblast-like phenotype. Accordingly, the overexpression of Cygb reduces extracellular matrix deposition in both toxic and cholestatic models of liver injury. The overexpression of Cygb also promotes recovery from previously initiated damage-induced fibrogenesis. By inhibiting free radical-induced activation of hepatic stellate cells, Cygb plays an important role in controlling tissue fibrosis. Therefore, the normal upregulation of Cygb during tissue injury has a homeostatic effect, inhibiting free radical-induced fibroblast activation and tissue fibrosis." @default.
• W2000917485 created "2016-06-24" @default.
• W2000917485 creator A5006423482 @default.
• W2000917485 creator A5008224304 @default.
• W2000917485 creator A5011573172 @default.
• W2000917485 creator A5012507632 @default.
• W2000917485 creator A5015449610 @default.
• W2000917485 creator A5039833572 @default.
• W2000917485 creator A5039896971 @default.
• W2000917485 creator A5043068272 @default.
• W2000917485 creator A5057770837 @default.
• W2000917485 creator A5068516295 @default.
• W2000917485 creator A5074186579 @default.
• W2000917485 creator A5077660989 @default.
• W2000917485 creator A5085011088 @default.
• W2000917485 date "2006-06-01" @default.
• W2000917485 modified "2023-10-10" @default.
• W2000917485 title "Cytoglobin Overexpression Protects against Damage-Induced Fibrosis" @default.
• W2000917485 cites W1507703835 @default.
• W2000917485 cites W1529656734 @default.
• W2000917485 cites W1653986885 @default.
• W2000917485 cites W1967773801 @default.
• W2000917485 cites W1969133067 @default.
• W2000917485 cites W1973737245 @default.
• W2000917485 cites W1983172504 @default.
• W2000917485 cites W1987398418 @default.
• W2000917485 cites W1988936361 @default.
• W2000917485 cites W1989528698 @default.
• W2000917485 cites W1997064567 @default.
• W2000917485 cites W2007476858 @default.
• W2000917485 cites W2031122915 @default.
• W2000917485 cites W2039370814 @default.
• W2000917485 cites W2042057179 @default.
• W2000917485 cites W2058409230 @default.
• W2000917485 cites W2059624242 @default.
• W2000917485 cites W2062510144 @default.
• W2000917485 cites W2069773991 @default.
• W2000917485 cites W2072115406 @default.
• W2000917485 cites W2094410857 @default.
• W2000917485 cites W2099711702 @default.
• W2000917485 cites W2154725664 @default.
• W2000917485 cites W2164923948 @default.
• W2000917485 cites W2321725396 @default.
• W2000917485 cites W4234984279 @default.
• W2000917485 cites W4250007760 @default.
• W2000917485 doi "https://doi.org/10.1016/j.ymthe.2005.11.027" @default.
• W2000917485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16581302" @default.
• W2000917485 hasPublicationYear "2006" @default.
• W2000917485 type Work @default.
• W2000917485 sameAs 2000917485 @default.
• W2000917485 citedByCount "89" @default.
• W2000917485 countsByYear W20009174852012 @default.
• W2000917485 countsByYear W20009174852013 @default.
• W2000917485 countsByYear W20009174852014 @default.
• W2000917485 countsByYear W20009174852015 @default.
• W2000917485 countsByYear W20009174852016 @default.
• W2000917485 countsByYear W20009174852017 @default.
• W2000917485 countsByYear W20009174852018 @default.
• W2000917485 countsByYear W20009174852019 @default.
• W2000917485 countsByYear W20009174852020 @default.
• W2000917485 countsByYear W20009174852021 @default.
• W2000917485 countsByYear W20009174852022 @default.
• W2000917485 countsByYear W20009174852023 @default.
• W2000917485 crossrefType "journal-article" @default.
• W2000917485 hasAuthorship W2000917485A5006423482 @default.
• W2000917485 hasAuthorship W2000917485A5008224304 @default.
• W2000917485 hasAuthorship W2000917485A5011573172 @default.
• W2000917485 hasAuthorship W2000917485A5012507632 @default.
• W2000917485 hasAuthorship W2000917485A5015449610 @default.
• W2000917485 hasAuthorship W2000917485A5039833572 @default.
• W2000917485 hasAuthorship W2000917485A5039896971 @default.
• W2000917485 hasAuthorship W2000917485A5043068272 @default.
• W2000917485 hasAuthorship W2000917485A5057770837 @default.
• W2000917485 hasAuthorship W2000917485A5068516295 @default.
• W2000917485 hasAuthorship W2000917485A5074186579 @default.
• W2000917485 hasAuthorship W2000917485A5077660989 @default.
• W2000917485 hasAuthorship W2000917485A5085011088 @default.
• W2000917485 hasBestOaLocation W20009174851 @default.
• W2000917485 hasConcept C104317684 @default.
• W2000917485 hasConcept C127561419 @default.
• W2000917485 hasConcept C134018914 @default.
• W2000917485 hasConcept C142724271 @default.
• W2000917485 hasConcept C176891718 @default.
• W2000917485 hasConcept C178790620 @default.
• W2000917485 hasConcept C181199279 @default.
• W2000917485 hasConcept C185592680 @default.
• W2000917485 hasConcept C189165786 @default.
• W2000917485 hasConcept C207865475 @default.
• W2000917485 hasConcept C2776151105 @default.
• W2000917485 hasConcept C2778784160 @default.
• W2000917485 hasConcept C2780559512 @default.
• W2000917485 hasConcept C2780795997 @default.
• W2000917485 hasConcept C2993667909 @default.
• W2000917485 hasConcept C502942594 @default.
• W2000917485 hasConcept C519581460 @default.
• W2000917485 hasConcept C55493867 @default.
• W2000917485 hasConcept C71924100 @default.
• W2000917485 hasConcept C86803240 @default.

• next