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- W2000917518 abstract "4-[N-(5, 6, 7, 8-Tetrahydro-5, 5, 8, 8-tetramethyl-2-naphthyl)amino]benzoic acid (5) exhibited weak retinoidal and retinoid synergistic activities in HL-60 cell differentiation assay. N-Alkylation of 5 caused decrease or loss or differentiation-inducing activity, but enhanced the synergistic activity with a synthetic retinoid Am80 (2), as reflected in the potent synergistic EC50 (SEC50) values of DA023 (11, 1.6×10-10 M) and DA113 (14, 1.4×10-10 M) in the presence of 1.0×10-10 M Am80 (2)." @default.
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- W2000917518 date "1998-01-01" @default.
- W2000917518 modified "2023-10-12" @default.
- W2000917518 title "Potent Retinoid Synergists with a Diphenylamine Skeleton." @default.
- W2000917518 doi "https://doi.org/10.1248/bpb.21.544" @default.
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