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- W2000917894 abstract "A single-chained protein designated solenin was isolated from Solenognathus hardwickii, a fish used as traditional Chinese medicinal material. Solenin was capable of inhibiting translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 2 μM and expressing a ribonuclease activity of 0.8 U/mg toward yeast transfer RNA, but it lacked N-glycosidase activity characteristic of ribosome inactivating proteins Solenin exhibited a molecular weight of 18 kDa and possessed an N-terminal sequence AHDAEVNEVKAQVAA. The protein was adsorbed on three types of chromatographic media: Affi-gel blue gel, CM-Sepharose and Mono S. It was devoid of antifungal and lectin activities." @default.
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- W2000917894 date "2002-06-01" @default.
- W2000917894 modified "2023-09-26" @default.
- W2000917894 title "Solenin, a novel protein with translation-inhibiting activity from the traditional Chinese medicinal fish, the sea dragon Solenognathus hardwickii" @default.
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- W2000917894 doi "https://doi.org/10.1016/s1357-2725(02)00003-1" @default.
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