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• W2000923521 abstract "<b>Objective</b> To compare the effectiveness of the oxytocin receptor antagonist atosiban with the beta mimetic fenoterol as uterine relaxants in women undergoing external cephalic version (ECV) for breech presentation. <b>Design</b> Multicentre, open label, randomised controlled trial. <b>Setting</b> Eight hospitals in the Netherlands, August 2009 to May 2014. <b>Participants</b> 830 women with a singleton fetus in breech presentation and a gestational age of more than 34 weeks were randomly allocated in a 1:1 ratio to either 6.75 mg atosiban (n=416) or 40 μg fenoterol (n=414) intravenously for uterine relaxation before ECV. <b>Main outcome measures</b> The primary outcome measures were a fetus in cephalic position 30 minutes after the procedure and cephalic presentation at delivery. Secondary outcome measures were mode of delivery, incidence of fetal and maternal complications, and drug related adverse events. All analyses were done on an intention-to-treat basis. <b>Results</b> Cephalic position 30 minutes after ECV occurred significantly less in the atosiban group than in the fenoterol group (34% <i>v</i> 40%, relative risk 0.73, 95% confidence interval 0.55 to 0.93). Presentation at birth was cephalic in 35% (n=139) of the atosiban group and 40% (n=166) of the fenoterol group (0.86, 0.72 to 1.03), and caesarean delivery was performed in 60% (n=240) of women in the atosiban group and 55% (n=218) in the fenoterol group (1.09, 0.96 to 1.20). No significant differences were found in neonatal outcomes or drug related adverse events. <b>Conclusions</b> In women undergoing ECV for breech presentation, uterine relaxation with fenoterol increases the rate of cephalic presentation 30 minutes after the procedure. No statistically significant difference was found for cephalic presentation at delivery. <b>Trial registration</b> Dutch Trial Register, NTR 1877." @default.
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• W2000923521 title "Abnormal Glomerular Filtration Rate, Renal Plasma Flow, and Renal Protein Excretion in Recent and Short-term Diabetics" @default.
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• W2000923521 doi "https://doi.org/10.1136/bmj.2.5804.13" @default.
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