Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000923922> ?p ?o ?g. }
- W2000923922 endingPage "48" @default.
- W2000923922 startingPage "42" @default.
- W2000923922 abstract "Macromolecular assembly and generation of serine proteases on cellular surfaces is critically invloved in regulation of hemostatic, inflammatory, or fibrinolytic pathways. The concept that a number of these serine proteases may effect cellular activation and proliferative responses has engendered an emerging paradigm focusing on the molecular mechanisms regulating cellular/protease interactions. Previous data suggest that some of these cellular responses are mediated by a novel class of G protein-coupled proteolytically activated receptors. Proteolytically activated receptor-3 (PAR-3) is the third member of this rapidly emerging gene family, all three of which (PAR-1, PAR-2, PAR-3) are known to co-cluster in the human genome, and are expressed on vascular endothelial cells, cells which critically regulate the hemostatic repertoire. This review will focus on the genetics of these receptors (emphasizing recent advances in the identification and characterization of PAR-3), review known structure/function similarities, and outline potential links in regulation of the hemostatic response by protease generation on the endothelial cell surface." @default.
- W2000923922 created "2016-06-24" @default.
- W2000923922 creator A5014274785 @default.
- W2000923922 creator A5014485759 @default.
- W2000923922 creator A5017802272 @default.
- W2000923922 date "1999-02-01" @default.
- W2000923922 modified "2023-10-11" @default.
- W2000923922 title "Proteolytically Activated Receptor-3 A Member of an Emerging Gene Family of Protease Receptors Expressed on Vascular Endothelial Cells and Platelets" @default.
- W2000923922 cites W1488156116 @default.
- W2000923922 cites W1529873450 @default.
- W2000923922 cites W1545475398 @default.
- W2000923922 cites W1658287483 @default.
- W2000923922 cites W1964456661 @default.
- W2000923922 cites W1964499190 @default.
- W2000923922 cites W1967307606 @default.
- W2000923922 cites W1974052300 @default.
- W2000923922 cites W1979557307 @default.
- W2000923922 cites W1985375673 @default.
- W2000923922 cites W1993059268 @default.
- W2000923922 cites W2016830520 @default.
- W2000923922 cites W2026151657 @default.
- W2000923922 cites W2031387417 @default.
- W2000923922 cites W2033629898 @default.
- W2000923922 cites W2039265075 @default.
- W2000923922 cites W2040540681 @default.
- W2000923922 cites W2043526402 @default.
- W2000923922 cites W2055043387 @default.
- W2000923922 cites W2069175943 @default.
- W2000923922 cites W2069611627 @default.
- W2000923922 cites W2074486895 @default.
- W2000923922 cites W2075331103 @default.
- W2000923922 cites W2081753893 @default.
- W2000923922 cites W2090371338 @default.
- W2000923922 cites W2097344561 @default.
- W2000923922 cites W2106882534 @default.
- W2000923922 cites W2153181138 @default.
- W2000923922 cites W2155865600 @default.
- W2000923922 cites W2276204843 @default.
- W2000923922 cites W2320161882 @default.
- W2000923922 cites W2366655530 @default.
- W2000923922 cites W2374117022 @default.
- W2000923922 cites W2394831682 @default.
- W2000923922 cites W2407525502 @default.
- W2000923922 cites W2471695409 @default.
- W2000923922 cites W44680899 @default.
- W2000923922 cites W89318376 @default.
- W2000923922 doi "https://doi.org/10.1016/s1050-1738(99)00005-5" @default.
- W2000923922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10189966" @default.
- W2000923922 hasPublicationYear "1999" @default.
- W2000923922 type Work @default.
- W2000923922 sameAs 2000923922 @default.
- W2000923922 citedByCount "35" @default.
- W2000923922 countsByYear W20009239222012 @default.
- W2000923922 countsByYear W20009239222015 @default.
- W2000923922 countsByYear W20009239222020 @default.
- W2000923922 countsByYear W20009239222021 @default.
- W2000923922 crossrefType "journal-article" @default.
- W2000923922 hasAuthorship W2000923922A5014274785 @default.
- W2000923922 hasAuthorship W2000923922A5014485759 @default.
- W2000923922 hasAuthorship W2000923922A5017802272 @default.
- W2000923922 hasConcept C104317684 @default.
- W2000923922 hasConcept C149577978 @default.
- W2000923922 hasConcept C170493617 @default.
- W2000923922 hasConcept C181199279 @default.
- W2000923922 hasConcept C182220744 @default.
- W2000923922 hasConcept C203014093 @default.
- W2000923922 hasConcept C2776714187 @default.
- W2000923922 hasConcept C2777292125 @default.
- W2000923922 hasConcept C2777807008 @default.
- W2000923922 hasConcept C54355233 @default.
- W2000923922 hasConcept C55493867 @default.
- W2000923922 hasConcept C86803240 @default.
- W2000923922 hasConcept C89560881 @default.
- W2000923922 hasConcept C95444343 @default.
- W2000923922 hasConceptScore W2000923922C104317684 @default.
- W2000923922 hasConceptScore W2000923922C149577978 @default.
- W2000923922 hasConceptScore W2000923922C170493617 @default.
- W2000923922 hasConceptScore W2000923922C181199279 @default.
- W2000923922 hasConceptScore W2000923922C182220744 @default.
- W2000923922 hasConceptScore W2000923922C203014093 @default.
- W2000923922 hasConceptScore W2000923922C2776714187 @default.
- W2000923922 hasConceptScore W2000923922C2777292125 @default.
- W2000923922 hasConceptScore W2000923922C2777807008 @default.
- W2000923922 hasConceptScore W2000923922C54355233 @default.
- W2000923922 hasConceptScore W2000923922C55493867 @default.
- W2000923922 hasConceptScore W2000923922C86803240 @default.
- W2000923922 hasConceptScore W2000923922C89560881 @default.
- W2000923922 hasConceptScore W2000923922C95444343 @default.
- W2000923922 hasIssue "1-2" @default.
- W2000923922 hasLocation W20009239221 @default.
- W2000923922 hasLocation W20009239222 @default.
- W2000923922 hasOpenAccess W2000923922 @default.
- W2000923922 hasPrimaryLocation W20009239221 @default.
- W2000923922 hasRelatedWork W1519327654 @default.
- W2000923922 hasRelatedWork W1749972705 @default.
- W2000923922 hasRelatedWork W1976128446 @default.
- W2000923922 hasRelatedWork W2016799856 @default.
- W2000923922 hasRelatedWork W2047128734 @default.