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• W2000925970 abstract "To determine if low levels of serum vitamin A and β-carotene are present in pregnant women with human immunodeficiency virus-1 (HIV-1) infection. Serum concentrations of vitamin A and β-carotene were measured in 74 pregnant women seropositive for HIV-1 infection (17 with CD4 count below 200 cells/μL) and in 148 pregnant seronegative controls in the first trimester. Comparisons were made between groups stratified by CD4 count. Compared with controls, women with HIV-1 infection and CD4 count below 200 cells/μL exhibited 37% lower mean serum vitamin A levels (0.820 versus 1.308 μmol/L, P < .001) and 37% lower mean serum β-carotene levels (1.486 versus 2.362 μmol/L, P < .001). Mean maternal age, parity, gestational age, hemoglobin levels, and body mass index at entry into the study did not differ significantly between the control and HIV-1 infection groups. In addition, serum vitamin A levels correlated significantly with the percentage of CD4 lymphocytes (r = 0.589, P < .001), CD4 count (r=0.772, P < .001), and CD4 to CD8 ratio (r=0.593, P < .001). Serum β-carotene levels correlated with the percentage of CD4 lymphocytes (r=0.407, P < .001), CD4 count (r=0.614, P < .001), and CD4 to CD8 ratio (r=0.434, P < .001). Compared with levels in uninfected women, serum vitamin A and β-carotene are decreased in HIV-1-infected pregnant women in the first trimester with CD4 counts lower than 200 cells/gmL. These micronutrient concentrations also correlate with CD4 count." @default.
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• W2000925970 date "1996-04-01" @default.
• W2000925970 modified "2023-10-11" @default.
• W2000925970 title "Serum vitamin a and β-carotene levels in pregnant women infected with human immunodeficiency virus-1" @default.
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• W2000925970 doi "https://doi.org/10.1016/0029-7844(95)00459-9" @default.
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