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- W2000929191 abstract "This study examined the reinforcing properties of dynorphin A (1-13) in a single-trial classical conditioning paradigm in the E20 rat fetus. Injection of dynorphin into the cisterna magna increased fetal motor activity and reduced facial wiping in a test of perioral cutaneous responsiveness. Dynorphin was effective as an unconditioned stimulus (US) in a classical conditioning paradigm using an artificial nipple conditioned stimulus (CS) and dynorphin A (1-13) US. The association between CS and US was dependent on activity in the kappa opioid system. Re-exposure to the artificial nipple CS after a single pairing of the nipple with dynorphin resulted in conditioned activation of the kappa opioid system. Dynorphin A (1-13) functions as a reinforcer for classical conditioning in the rat fetus after intracisternal or intrahemispheric injection, with the conditioned response depending on route of administration and site of injection." @default.
- W2000929191 created "2016-06-24" @default.
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- W2000929191 date "1996-01-01" @default.
- W2000929191 modified "2023-10-16" @default.
- W2000929191 title "Classical conditioning in the fetal rat: Reinforcing properties of dynorphin A (1-13)." @default.
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- W2000929191 doi "https://doi.org/10.1037//0735-7044.110.1.154" @default.
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