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- W2000931539 abstract "This paper presents an environmentally improved procedure for the preparative purification of a series of arginine-based gemini surfactants. The technique used was cation-exchange chromatography. Mixtures of boric-borate buffer, co-solvent (ethanol), and sodium chloride were tested as eluents. The influence of the buffer pH and the amount of co-solvent on the chromatographic process was studied for the model compound bis(Nα-lauroyl-L-arginine)1,3-propanediamide dihydrochloride, C3(LA)2, and purification conditions were established. The method was scaled-up to the multigram level for C3(LA)2 and the rest of the series. The proposed preparative procedure involves simple equipment, low cost materials, and minimal amounts of solvent (water/ethanol), with low toxicity." @default.
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- W2000931539 date "2001-07-31" @default.
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- W2000931539 title "PURIFICATION OF NON-TOXIC, BIODEGRADABLE ARGININE-BASED GEMINI SURFACTANTS, BIS(ARGS), BY ION EXCHANGE CHROMATOGRAPHY" @default.
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- W2000931539 doi "https://doi.org/10.1081/pb-100104908" @default.
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