Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000933122> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2000933122 endingPage "66" @default.
- W2000933122 startingPage "47" @default.
- W2000933122 abstract "In this work we studied the effects of the molecular weight (M.W.) of thyroxin (T4)-conjugates and the sample dilution factor on the binding potential (C) of serum T4-binding proteins for these T4-conjugates. We prepared six T4-conjugates with great difference in molecular weight with proteins such as IgG, apoferritin, ferritin, transferrin, and thyroglobulin using p-benzoquinone as bifunctional reagent. The conjugates prepared were characterized in terms of their M.W., the molar ratio of T4 to the carrier protein, and their affinity to bind with the anti-Tr antibody. The binding potential values of serum T4-binding proteins for the T4-conjugates were determined, following appropriate mathematical interpretation of the results, obtained through an assay system containing 125I-labeled conjugated tracers, anti-T4 antibody in great excess compared with the concentration of the tracers, and increasing concentration of T4-binding proteins. We conclude that the M.W. of the conjugates is a parameter which significantly influences the binding of a conjugate to the T4-binding proteins. Additionally, for conjugates of very high M.W. (> 650,000), zero C values were obtained using 20-fold sample dilution in the final incubation mixture." @default.
- W2000933122 created "2016-06-24" @default.
- W2000933122 creator A5017118977 @default.
- W2000933122 creator A5019691929 @default.
- W2000933122 date "1996-02-01" @default.
- W2000933122 modified "2023-09-30" @default.
- W2000933122 title "Study of Binding of Thyroxin-Conjugates to the Thyroxin-Binding Proteins" @default.
- W2000933122 cites W1863964903 @default.
- W2000933122 cites W1866280982 @default.
- W2000933122 cites W1927253507 @default.
- W2000933122 cites W1949481233 @default.
- W2000933122 cites W2005183867 @default.
- W2000933122 cites W2089260559 @default.
- W2000933122 cites W2102131116 @default.
- W2000933122 cites W2152300932 @default.
- W2000933122 cites W2163480387 @default.
- W2000933122 cites W2166859748 @default.
- W2000933122 cites W2291353066 @default.
- W2000933122 cites W2405768423 @default.
- W2000933122 cites W4252669799 @default.
- W2000933122 cites W4299953928 @default.
- W2000933122 doi "https://doi.org/10.1080/01971529608005778" @default.
- W2000933122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8926306" @default.
- W2000933122 hasPublicationYear "1996" @default.
- W2000933122 type Work @default.
- W2000933122 sameAs 2000933122 @default.
- W2000933122 citedByCount "3" @default.
- W2000933122 crossrefType "journal-article" @default.
- W2000933122 hasAuthorship W2000933122A5017118977 @default.
- W2000933122 hasAuthorship W2000933122A5019691929 @default.
- W2000933122 hasConcept C107824862 @default.
- W2000933122 hasConcept C121332964 @default.
- W2000933122 hasConcept C134306372 @default.
- W2000933122 hasConcept C146543888 @default.
- W2000933122 hasConcept C159654299 @default.
- W2000933122 hasConcept C185592680 @default.
- W2000933122 hasConcept C197336794 @default.
- W2000933122 hasConcept C203014093 @default.
- W2000933122 hasConcept C22814914 @default.
- W2000933122 hasConcept C2778319317 @default.
- W2000933122 hasConcept C2778835679 @default.
- W2000933122 hasConcept C33923547 @default.
- W2000933122 hasConcept C43617362 @default.
- W2000933122 hasConcept C51639874 @default.
- W2000933122 hasConcept C55493867 @default.
- W2000933122 hasConcept C86803240 @default.
- W2000933122 hasConcept C96618451 @default.
- W2000933122 hasConcept C97355855 @default.
- W2000933122 hasConceptScore W2000933122C107824862 @default.
- W2000933122 hasConceptScore W2000933122C121332964 @default.
- W2000933122 hasConceptScore W2000933122C134306372 @default.
- W2000933122 hasConceptScore W2000933122C146543888 @default.
- W2000933122 hasConceptScore W2000933122C159654299 @default.
- W2000933122 hasConceptScore W2000933122C185592680 @default.
- W2000933122 hasConceptScore W2000933122C197336794 @default.
- W2000933122 hasConceptScore W2000933122C203014093 @default.
- W2000933122 hasConceptScore W2000933122C22814914 @default.
- W2000933122 hasConceptScore W2000933122C2778319317 @default.
- W2000933122 hasConceptScore W2000933122C2778835679 @default.
- W2000933122 hasConceptScore W2000933122C33923547 @default.
- W2000933122 hasConceptScore W2000933122C43617362 @default.
- W2000933122 hasConceptScore W2000933122C51639874 @default.
- W2000933122 hasConceptScore W2000933122C55493867 @default.
- W2000933122 hasConceptScore W2000933122C86803240 @default.
- W2000933122 hasConceptScore W2000933122C96618451 @default.
- W2000933122 hasConceptScore W2000933122C97355855 @default.
- W2000933122 hasIssue "1" @default.
- W2000933122 hasLocation W20009331221 @default.
- W2000933122 hasLocation W20009331222 @default.
- W2000933122 hasOpenAccess W2000933122 @default.
- W2000933122 hasPrimaryLocation W20009331221 @default.
- W2000933122 hasRelatedWork W1551691785 @default.
- W2000933122 hasRelatedWork W1990068946 @default.
- W2000933122 hasRelatedWork W2000933122 @default.
- W2000933122 hasRelatedWork W2003140491 @default.
- W2000933122 hasRelatedWork W2063359791 @default.
- W2000933122 hasRelatedWork W2072159717 @default.
- W2000933122 hasRelatedWork W2077087696 @default.
- W2000933122 hasRelatedWork W2150649413 @default.
- W2000933122 hasRelatedWork W2163571668 @default.
- W2000933122 hasRelatedWork W2030769768 @default.
- W2000933122 hasVolume "17" @default.
- W2000933122 isParatext "false" @default.
- W2000933122 isRetracted "false" @default.
- W2000933122 magId "2000933122" @default.
- W2000933122 workType "article" @default.