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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000933223> ?p ?o ?g. }

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• W2000933223 abstract "We have designed and evaluated the performance of a simple, rapid, and affordable method for counting CD4(+) T-cells with the use of plastic microchips. This new system is an adaptation of a no-lyse, no-wash, volumetric single platform assay, and absolute CD4(+) counts are determined with the use of a microscopic scanning cell counter. To assess the CD4(+) count test precision and linearity of the system, measured CD4(+) counts were compared with two other reference assays (single and dual platform flow cytometry) with the use of 123 clinical samples including samples obtained from 35 HIV-infected patients, and artificially diluted samples. A correlation between the results from the use of the new method and from the use of the two other reference assays was r = 0.98 for the clinical samples. A dilution test of the new method demonstrated a linearity of r >or= 0.99, with coefficients of variation <or=7.6% for all concentration levels. Our findings suggest that the new CD4(+) counting device can be potentially be applied for other diagnostic procedures that measure quantities of characteristic antigens or other materials on cells." @default.
• W2000933223 created "2016-06-24" @default.
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• W2000933223 date "2009-09-01" @default.
• W2000933223 modified "2023-10-16" @default.
• W2000933223 title "Absolute CD4+cell count using a plastic microchip and a microscopic cell counter" @default.
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• W2000933223 doi "https://doi.org/10.1002/cyto.b.20470" @default.
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