Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000935163> ?p ?o ?g. }
- W2000935163 endingPage "147" @default.
- W2000935163 startingPage "140" @default.
- W2000935163 abstract "Diallyl disulfide (DADS) is an organosulfur compound from garlic which exhibits various anticarcinogenic properties including inhibition of tumor cell proliferation. DADS antiproliferative effects were previously associated with an increase in histone acetylation in two human tumor colon cell lines, suggesting that DADS-induced histone hyperacetylation could be one of the mechanisms involved in its protective properties on colon carcinogenesis. The effects of DADS on histone H4 and H3 acetylation levels were investigated in vivo in colonocytes isolated from non-tumoral rat. Administrated by intracaecal perfusion or gavage, DADS increases histone H4 and H3 acetylation in colonocytes. Moreover, data generated using cDNA expression arrays suggest that DADS could modulate the expression of a subset of genes. These results suggest the involvement of histone acetylation in modulation of gene expression by DADS in normal rat colonocytes, which might play a role in its biological effects as well as in its anticarcinogenic properties in vivo." @default.
- W2000935163 created "2016-06-24" @default.
- W2000935163 creator A5021381524 @default.
- W2000935163 creator A5028223956 @default.
- W2000935163 creator A5032837946 @default.
- W2000935163 creator A5039979792 @default.
- W2000935163 creator A5060383645 @default.
- W2000935163 creator A5073786422 @default.
- W2000935163 creator A5079765812 @default.
- W2000935163 creator A5085377597 @default.
- W2000935163 creator A5088855357 @default.
- W2000935163 date "2007-03-01" @default.
- W2000935163 modified "2023-10-14" @default.
- W2000935163 title "In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes" @default.
- W2000935163 cites W1665195032 @default.
- W2000935163 cites W1912102954 @default.
- W2000935163 cites W1985645100 @default.
- W2000935163 cites W1992907029 @default.
- W2000935163 cites W1996012806 @default.
- W2000935163 cites W1998761065 @default.
- W2000935163 cites W2008121938 @default.
- W2000935163 cites W2012659976 @default.
- W2000935163 cites W2014102496 @default.
- W2000935163 cites W2014736194 @default.
- W2000935163 cites W2015892667 @default.
- W2000935163 cites W2017953786 @default.
- W2000935163 cites W2085896858 @default.
- W2000935163 cites W2096886048 @default.
- W2000935163 cites W2115261967 @default.
- W2000935163 cites W2118593942 @default.
- W2000935163 cites W2126762394 @default.
- W2000935163 cites W2143175267 @default.
- W2000935163 cites W2153601430 @default.
- W2000935163 cites W2156279805 @default.
- W2000935163 cites W2157206580 @default.
- W2000935163 cites W2158798785 @default.
- W2000935163 cites W2159075571 @default.
- W2000935163 cites W2162321094 @default.
- W2000935163 cites W2169658646 @default.
- W2000935163 cites W2171382468 @default.
- W2000935163 doi "https://doi.org/10.1016/j.bbrc.2006.12.158" @default.
- W2000935163 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17210128" @default.
- W2000935163 hasPublicationYear "2007" @default.
- W2000935163 type Work @default.
- W2000935163 sameAs 2000935163 @default.
- W2000935163 citedByCount "46" @default.
- W2000935163 countsByYear W20009351632012 @default.
- W2000935163 countsByYear W20009351632013 @default.
- W2000935163 countsByYear W20009351632014 @default.
- W2000935163 countsByYear W20009351632015 @default.
- W2000935163 countsByYear W20009351632016 @default.
- W2000935163 countsByYear W20009351632017 @default.
- W2000935163 countsByYear W20009351632018 @default.
- W2000935163 countsByYear W20009351632021 @default.
- W2000935163 countsByYear W20009351632022 @default.
- W2000935163 countsByYear W20009351632023 @default.
- W2000935163 crossrefType "journal-article" @default.
- W2000935163 hasAuthorship W2000935163A5021381524 @default.
- W2000935163 hasAuthorship W2000935163A5028223956 @default.
- W2000935163 hasAuthorship W2000935163A5032837946 @default.
- W2000935163 hasAuthorship W2000935163A5039979792 @default.
- W2000935163 hasAuthorship W2000935163A5060383645 @default.
- W2000935163 hasAuthorship W2000935163A5073786422 @default.
- W2000935163 hasAuthorship W2000935163A5079765812 @default.
- W2000935163 hasAuthorship W2000935163A5085377597 @default.
- W2000935163 hasAuthorship W2000935163A5088855357 @default.
- W2000935163 hasConcept C104317684 @default.
- W2000935163 hasConcept C119157956 @default.
- W2000935163 hasConcept C150194340 @default.
- W2000935163 hasConcept C153911025 @default.
- W2000935163 hasConcept C185592680 @default.
- W2000935163 hasConcept C190283241 @default.
- W2000935163 hasConcept C207001950 @default.
- W2000935163 hasConcept C2776488830 @default.
- W2000935163 hasConcept C2776745794 @default.
- W2000935163 hasConcept C2779085176 @default.
- W2000935163 hasConcept C41091548 @default.
- W2000935163 hasConcept C502942594 @default.
- W2000935163 hasConcept C54355233 @default.
- W2000935163 hasConcept C55493867 @default.
- W2000935163 hasConcept C62112901 @default.
- W2000935163 hasConcept C64927066 @default.
- W2000935163 hasConcept C86803240 @default.
- W2000935163 hasConcept C95444343 @default.
- W2000935163 hasConceptScore W2000935163C104317684 @default.
- W2000935163 hasConceptScore W2000935163C119157956 @default.
- W2000935163 hasConceptScore W2000935163C150194340 @default.
- W2000935163 hasConceptScore W2000935163C153911025 @default.
- W2000935163 hasConceptScore W2000935163C185592680 @default.
- W2000935163 hasConceptScore W2000935163C190283241 @default.
- W2000935163 hasConceptScore W2000935163C207001950 @default.
- W2000935163 hasConceptScore W2000935163C2776488830 @default.
- W2000935163 hasConceptScore W2000935163C2776745794 @default.
- W2000935163 hasConceptScore W2000935163C2779085176 @default.
- W2000935163 hasConceptScore W2000935163C41091548 @default.
- W2000935163 hasConceptScore W2000935163C502942594 @default.
- W2000935163 hasConceptScore W2000935163C54355233 @default.
- W2000935163 hasConceptScore W2000935163C55493867 @default.