FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000938346> ?p ?o ?g. }

• W2000938346 endingPage "267" @default.
• W2000938346 startingPage "257" @default.
• W2000938346 abstract "There is accumulating evidence that the dorsomedial striatum plays a significant role in the learning of a new response pattern and the inhibiting of old response patterns when conditions demand a shift in strategies. This paper proposes that activity of cholinergic neurons in the dorsomedial striatum is critical for enabling behavioral flexibility when there is a change in task contingencies. Recent experimental findings are provided supporting this idea. Measuring acetylcholine efflux from the dorsomedial striatum during the acquisition and reversal learning of a spatial discrimination shows that acetylcholine efflux selectively increases during reversal learning as a rat begins to learn a newly reinforced spatial location, but returns to near basal levels when a rat reliably executes the new choice pattern. Experimental findings are also described indicating that the blockade of muscarinic cholinergic receptors in the dorsomedial striatum does not impair acquisition of an egocentric response discrimination, but impairs reversal learning of an egocentric response discrimination. Based on these results, increased cholinergic activity at muscarinic receptors is part of a neurochemical process in the dorsomedial striatum that allows inhibition of a previously relevant response pattern while learning a new response pattern. In situations that demand behavioral flexibility, muscarinic cholinergic activity in the dorsomedial striatum may directly influence corticostriatal plasticity to produce changes in response patterns." @default.
• W2000938346 created "2016-06-24" @default.
• W2000938346 creator A5002119822 @default.
• W2000938346 date "2003-11-01" @default.
• W2000938346 modified "2023-09-25" @default.
• W2000938346 title "Acetylcholine actions in the dorsomedial striatum support the flexible shifting of response patterns" @default.
• W2000938346 cites W1503090542 @default.
• W2000938346 cites W1517292608 @default.
• W2000938346 cites W1543271211 @default.
• W2000938346 cites W1549437185 @default.
• W2000938346 cites W1600793774 @default.
• W2000938346 cites W1622774380 @default.
• W2000938346 cites W1776364276 @default.
• W2000938346 cites W1867720884 @default.
• W2000938346 cites W1910271824 @default.
• W2000938346 cites W1948130162 @default.
• W2000938346 cites W1964060360 @default.
• W2000938346 cites W1979300762 @default.
• W2000938346 cites W1985938249 @default.
• W2000938346 cites W1987755799 @default.
• W2000938346 cites W1987996701 @default.
• W2000938346 cites W1991101029 @default.
• W2000938346 cites W1994127211 @default.
• W2000938346 cites W1994986930 @default.
• W2000938346 cites W1998664518 @default.
• W2000938346 cites W1998777125 @default.
• W2000938346 cites W1999362064 @default.
• W2000938346 cites W2004729128 @default.
• W2000938346 cites W2007442068 @default.
• W2000938346 cites W2010478807 @default.
• W2000938346 cites W2012483271 @default.
• W2000938346 cites W2013846355 @default.
• W2000938346 cites W2017386708 @default.
• W2000938346 cites W2032284808 @default.
• W2000938346 cites W2033904402 @default.
• W2000938346 cites W2046671791 @default.
• W2000938346 cites W2046713629 @default.
• W2000938346 cites W2057787317 @default.
• W2000938346 cites W2058658746 @default.
• W2000938346 cites W2060536327 @default.
• W2000938346 cites W2061471303 @default.
• W2000938346 cites W2062309855 @default.
• W2000938346 cites W2063764296 @default.
• W2000938346 cites W2064724496 @default.
• W2000938346 cites W2069310569 @default.
• W2000938346 cites W2070549053 @default.
• W2000938346 cites W2073408285 @default.
• W2000938346 cites W2073714333 @default.
• W2000938346 cites W2074320155 @default.
• W2000938346 cites W2076635082 @default.
• W2000938346 cites W2079480360 @default.
• W2000938346 cites W2085374324 @default.
• W2000938346 cites W2085899483 @default.
• W2000938346 cites W2086968795 @default.
• W2000938346 cites W2089025505 @default.
• W2000938346 cites W2090041950 @default.
• W2000938346 cites W2094108788 @default.
• W2000938346 cites W2104600915 @default.
• W2000938346 cites W2106598883 @default.
• W2000938346 cites W2110405906 @default.
• W2000938346 cites W2114554944 @default.
• W2000938346 cites W2116821483 @default.
• W2000938346 cites W2119392695 @default.
• W2000938346 cites W2134551595 @default.
• W2000938346 cites W2137739315 @default.
• W2000938346 cites W2138270641 @default.
• W2000938346 cites W2147122909 @default.
• W2000938346 cites W2148134595 @default.
• W2000938346 cites W2160999761 @default.
• W2000938346 cites W2190645785 @default.
• W2000938346 cites W2199533381 @default.
• W2000938346 cites W4230783006 @default.
• W2000938346 cites W4232431729 @default.
• W2000938346 cites W4232482461 @default.
• W2000938346 cites W4247603503 @default.
• W2000938346 doi "https://doi.org/10.1016/s1074-7427(03)00077-7" @default.
• W2000938346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14521868" @default.
• W2000938346 hasPublicationYear "2003" @default.
• W2000938346 type Work @default.
• W2000938346 sameAs 2000938346 @default.
• W2000938346 citedByCount "82" @default.
• W2000938346 countsByYear W20009383462012 @default.
• W2000938346 countsByYear W20009383462013 @default.
• W2000938346 countsByYear W20009383462014 @default.
• W2000938346 countsByYear W20009383462015 @default.
• W2000938346 countsByYear W20009383462016 @default.
• W2000938346 countsByYear W20009383462017 @default.
• W2000938346 countsByYear W20009383462018 @default.
• W2000938346 countsByYear W20009383462019 @default.
• W2000938346 countsByYear W20009383462020 @default.
• W2000938346 countsByYear W20009383462021 @default.
• W2000938346 countsByYear W20009383462022 @default.
• W2000938346 countsByYear W20009383462023 @default.
• W2000938346 crossrefType "journal-article" @default.
• W2000938346 hasAuthorship W2000938346A5002119822 @default.
• W2000938346 hasConcept C134018914 @default.
• W2000938346 hasConcept C15744967 @default.
• W2000938346 hasConcept C169760540 @default.

• next