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- W2000943659 abstract "The systolic time intervals (LVET, PEP, and ratio LVETPEP) were determined in 53 patients presenting with signs or symptoms of thyroid dysfunction. Patients with clinical evidence for congestive heart failure, with arterial hypertension or old myocardial infarction, and patients receiving cardioactive drugs were excluded from the study. Thyroid function was evaluated by means of T3-RIA, serum thyroxin, and TRH stimulation test. In patients with hyperthyroidism (untreated and on treatment), PEPc was shortened significantly (91.7 ± 11.0 msec. compared to a control of 118 ± 9.3 msex.). LVETc was prolonged only insignificantly. Hence, the ratio LVETcPEPc showed a significant increase in hyperthyroid patients. In hypothyroid patients (untreated and on treatment), PEPc was prolonged to 152.4 ± 15.1 msec. LVETc was shortened (399.7 ± 14.4 msec. compared to a control of 413.7 ± 15.9 msec.). The ratio LVETcPEPc was decreased. In seven patients, serial determinations of PEPc were performed; the values returned towards normal after successful treatment of thyroid dysfunction. A significant linear correlation between PEPc and T4 (r = −0.67) as well as LVETcPEPc and T4 (r = 0.64) was found. In 17 patients with hyperthyroidism and in eight patients with hypothyroidism 33 determinations of PEPc were performed. All but one of the values differed by at least 1 SD from our normal group, or, taking 2 SD, thyroid function could be evaluated correctly in approximately 75 per cent of patients." @default.
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- W2000943659 date "1978-02-01" @default.
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- W2000943659 title "The systolic time intervals in thyroid dysfunction" @default.
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- W2000943659 doi "https://doi.org/10.1016/0002-8703(78)90462-3" @default.
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