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- W2000946888 abstract "The ratio between 11 deoxy-17 ketosteroids and 17-hydroxycorticosteroids (Bulbrook's discriminant) and the ratio between pregnenetriol and pregnanetriol were measured in the urines of forty-one patients with advanced cancer of the breast. It was found that the two ratios were very significantly correlated. The ratio pregnenetriol/pregnanetriol reveals the efficiency of adrenal 3β hydroxysteroid dehydrogenase, an enzyme known to be blocked by oestrogens. It is therefore presumed that the Bulbrook's discriminant, of prognostic value in breast cancer patients, is an assessment of endogenous oestrogen effect." @default.
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- W2000946888 title "The urinary excretion of pregnanetriol and pregnenetriol in patients with breast cancer. A postulation on the meaning of Bulbrook's discriminant" @default.
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- W2000946888 doi "https://doi.org/10.1016/0014-2964(76)90008-6" @default.
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