Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000954226> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2000954226 endingPage "173" @default.
- W2000954226 startingPage "169" @default.
- W2000954226 abstract "Dexamethasone nano-aggregate was prepared for the treatment of intimal hyperplasia caused by abnormal proliferation of smooth muscle cells. Triblock copolymers composed of poly(ethylene glycol) [PEG] and poly(d,l-lactic acid) [PLA] were synthesized with different chain lengths of PEG. Triblock copolymers in organic phase were mixed with dexamethasone and dexamethasone nano-aggregates was prepared by dispersing the organic phase into water. The average diameter of the nano-aggregates ranged from 200 to 300 nm. Dexamethasone was released out from the nano-aggregates and the release profile was dependent on PEG chain lengths. The dexamethasone nano-aggregates showed superior anti-proliferation effects on smooth muscle cells compared to dexamethasone. Flow cytometry showed that smooth muscle cells treated with dexamethasone nano-aggregates was arrested at a dormant phase in a dose-dependent manner. The dexamethasone nano-aggregates are expected to be a potent candidate for anti-proliferating smooth muscle tissues after a balloon-catheter treatment." @default.
- W2000954226 created "2016-06-24" @default.
- W2000954226 creator A5033927749 @default.
- W2000954226 creator A5088688292 @default.
- W2000954226 date "2006-12-01" @default.
- W2000954226 modified "2023-09-26" @default.
- W2000954226 title "Dexamethasone nano-aggregates composed of PEG–PLA–PEG triblock copolymers for anti-proliferation of smooth muscle cells" @default.
- W2000954226 cites W1495785845 @default.
- W2000954226 cites W1800156099 @default.
- W2000954226 cites W1981089060 @default.
- W2000954226 cites W1999599133 @default.
- W2000954226 cites W1999903282 @default.
- W2000954226 cites W2003203475 @default.
- W2000954226 cites W2009749128 @default.
- W2000954226 cites W2015070193 @default.
- W2000954226 cites W2022139654 @default.
- W2000954226 cites W2025641548 @default.
- W2000954226 cites W2042664453 @default.
- W2000954226 cites W2048198014 @default.
- W2000954226 cites W2082667344 @default.
- W2000954226 cites W2094251934 @default.
- W2000954226 cites W2144773035 @default.
- W2000954226 doi "https://doi.org/10.1016/j.ijpharm.2006.06.041" @default.
- W2000954226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16889913" @default.
- W2000954226 hasPublicationYear "2006" @default.
- W2000954226 type Work @default.
- W2000954226 sameAs 2000954226 @default.
- W2000954226 citedByCount "20" @default.
- W2000954226 countsByYear W20009542262012 @default.
- W2000954226 countsByYear W20009542262013 @default.
- W2000954226 countsByYear W20009542262014 @default.
- W2000954226 countsByYear W20009542262015 @default.
- W2000954226 countsByYear W20009542262016 @default.
- W2000954226 countsByYear W20009542262017 @default.
- W2000954226 countsByYear W20009542262019 @default.
- W2000954226 countsByYear W20009542262020 @default.
- W2000954226 crossrefType "journal-article" @default.
- W2000954226 hasAuthorship W2000954226A5033927749 @default.
- W2000954226 hasAuthorship W2000954226A5088688292 @default.
- W2000954226 hasConcept C10138342 @default.
- W2000954226 hasConcept C12554922 @default.
- W2000954226 hasConcept C127413603 @default.
- W2000954226 hasConcept C134018914 @default.
- W2000954226 hasConcept C15920480 @default.
- W2000954226 hasConcept C159985019 @default.
- W2000954226 hasConcept C162324750 @default.
- W2000954226 hasConcept C178790620 @default.
- W2000954226 hasConcept C185592680 @default.
- W2000954226 hasConcept C192562407 @default.
- W2000954226 hasConcept C2777516009 @default.
- W2000954226 hasConcept C2780357685 @default.
- W2000954226 hasConcept C2780401358 @default.
- W2000954226 hasConcept C42360764 @default.
- W2000954226 hasConcept C521977710 @default.
- W2000954226 hasConcept C54400483 @default.
- W2000954226 hasConcept C71924100 @default.
- W2000954226 hasConcept C86803240 @default.
- W2000954226 hasConceptScore W2000954226C10138342 @default.
- W2000954226 hasConceptScore W2000954226C12554922 @default.
- W2000954226 hasConceptScore W2000954226C127413603 @default.
- W2000954226 hasConceptScore W2000954226C134018914 @default.
- W2000954226 hasConceptScore W2000954226C15920480 @default.
- W2000954226 hasConceptScore W2000954226C159985019 @default.
- W2000954226 hasConceptScore W2000954226C162324750 @default.
- W2000954226 hasConceptScore W2000954226C178790620 @default.
- W2000954226 hasConceptScore W2000954226C185592680 @default.
- W2000954226 hasConceptScore W2000954226C192562407 @default.
- W2000954226 hasConceptScore W2000954226C2777516009 @default.
- W2000954226 hasConceptScore W2000954226C2780357685 @default.
- W2000954226 hasConceptScore W2000954226C2780401358 @default.
- W2000954226 hasConceptScore W2000954226C42360764 @default.
- W2000954226 hasConceptScore W2000954226C521977710 @default.
- W2000954226 hasConceptScore W2000954226C54400483 @default.
- W2000954226 hasConceptScore W2000954226C71924100 @default.
- W2000954226 hasConceptScore W2000954226C86803240 @default.
- W2000954226 hasIssue "1-2" @default.
- W2000954226 hasLocation W20009542261 @default.
- W2000954226 hasLocation W20009542262 @default.
- W2000954226 hasOpenAccess W2000954226 @default.
- W2000954226 hasPrimaryLocation W20009542261 @default.
- W2000954226 hasRelatedWork W1972186585 @default.
- W2000954226 hasRelatedWork W2039527715 @default.
- W2000954226 hasRelatedWork W2042513326 @default.
- W2000954226 hasRelatedWork W2044901048 @default.
- W2000954226 hasRelatedWork W2046304784 @default.
- W2000954226 hasRelatedWork W2077315077 @default.
- W2000954226 hasRelatedWork W2145501107 @default.
- W2000954226 hasRelatedWork W2349407166 @default.
- W2000954226 hasRelatedWork W2358252049 @default.
- W2000954226 hasRelatedWork W2370127755 @default.
- W2000954226 hasVolume "326" @default.
- W2000954226 isParatext "false" @default.
- W2000954226 isRetracted "false" @default.
- W2000954226 magId "2000954226" @default.
- W2000954226 workType "article" @default.