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• W2000958565 abstract "The enantiomer of endomorphin-1 (Tyr-Pro-Trp-PheNH2) and the analogues containing (S)- or (R)-beta-proline have been synthesized, and their affinities towards mu-opioid receptors have been measured. As expected, the incubations of the different peptides with some commercially available enzymes showed that the presence of D-residues gave strong resistance towards digestion. The presence of beta-proline alone is sufficient to confer good resistance against the hydrolysis of the biologically strategic Pro-Trp bond." @default.
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• W2000958565 date "2003-03-27" @default.
• W2000958565 modified "2023-10-17" @default.
• W2000958565 title "Stability against enzymatic hydrolysis of endomorphin-1 analogues containing β-proline" @default.
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• W2000958565 doi "https://doi.org/10.1039/b301507f" @default.
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