Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000960276> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2000960276 endingPage "34" @default.
- W2000960276 startingPage "31" @default.
- W2000960276 abstract "To investigate whether bronchial C-fiber stimulation induced by capsaicin inhalation evokes nonadrenergic inhibitory (NAI) system bronchodilation, we studied partial and maximal expiratory flow-volume (PEFV and MEFV) curves in 5 normal subjects after inhalation of oxitropium bromide and propranolol. PGF2α (1 mg/ml inhaled for 5 min) was administered to induce bronchoconstriction. Then aerosolized capsaicin was inhaled (2.4 × 10−9 mol) to stimulate bronchial C-fibers. PGF2α produced significant bronchoconstriction; FEV1 and flow during a PEFV curve at 30% forced vital capacity (30p) decreased over a 15-min period. Capsaicin induced significant bronchodilation; 30p increased for 2 to 6 min (0.001 < p < 0.02), and FEV1 increased for 2 to 4 min (p < 0.05) when compared with saline-ethanol (vehicle of capsaicin) inhalation. After treatment with the ganglionic blocking agent hexamethonium, the significant bronchodilator response disappeared. These results suggest that the NAI system has a distinct bronchodilator action in human subjects in vivo , and that the bronchial C-fiber receptors may be involved in the reflex pathway for NAI system bronchodilation in humans." @default.
- W2000960276 created "2016-06-24" @default.
- W2000960276 creator A5007157113 @default.
- W2000960276 creator A5011469729 @default.
- W2000960276 creator A5048387742 @default.
- W2000960276 creator A5065479085 @default.
- W2000960276 date "1988-07-01" @default.
- W2000960276 modified "2023-09-25" @default.
- W2000960276 title "Nonadrenergic Bronchodilation in Normal Subjects" @default.
- W2000960276 cites W1924475567 @default.
- W2000960276 cites W1966798093 @default.
- W2000960276 cites W2016437018 @default.
- W2000960276 cites W2052644642 @default.
- W2000960276 cites W2101824849 @default.
- W2000960276 cites W2104324332 @default.
- W2000960276 cites W2107433166 @default.
- W2000960276 cites W2157131580 @default.
- W2000960276 cites W2175156825 @default.
- W2000960276 cites W2183711443 @default.
- W2000960276 doi "https://doi.org/10.1164/ajrccm/138.1.31" @default.
- W2000960276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3202398" @default.
- W2000960276 hasPublicationYear "1988" @default.
- W2000960276 type Work @default.
- W2000960276 sameAs 2000960276 @default.
- W2000960276 citedByCount "52" @default.
- W2000960276 countsByYear W20009602762012 @default.
- W2000960276 countsByYear W20009602762014 @default.
- W2000960276 crossrefType "journal-article" @default.
- W2000960276 hasAuthorship W2000960276A5007157113 @default.
- W2000960276 hasAuthorship W2000960276A5011469729 @default.
- W2000960276 hasAuthorship W2000960276A5048387742 @default.
- W2000960276 hasAuthorship W2000960276A5065479085 @default.
- W2000960276 hasConcept C105922876 @default.
- W2000960276 hasConcept C126322002 @default.
- W2000960276 hasConcept C170493617 @default.
- W2000960276 hasConcept C2776042228 @default.
- W2000960276 hasConcept C2776954882 @default.
- W2000960276 hasConcept C2778151854 @default.
- W2000960276 hasConcept C2780051329 @default.
- W2000960276 hasConcept C2780532441 @default.
- W2000960276 hasConcept C2780769369 @default.
- W2000960276 hasConcept C2781018748 @default.
- W2000960276 hasConcept C2908646376 @default.
- W2000960276 hasConcept C42219234 @default.
- W2000960276 hasConcept C71924100 @default.
- W2000960276 hasConceptScore W2000960276C105922876 @default.
- W2000960276 hasConceptScore W2000960276C126322002 @default.
- W2000960276 hasConceptScore W2000960276C170493617 @default.
- W2000960276 hasConceptScore W2000960276C2776042228 @default.
- W2000960276 hasConceptScore W2000960276C2776954882 @default.
- W2000960276 hasConceptScore W2000960276C2778151854 @default.
- W2000960276 hasConceptScore W2000960276C2780051329 @default.
- W2000960276 hasConceptScore W2000960276C2780532441 @default.
- W2000960276 hasConceptScore W2000960276C2780769369 @default.
- W2000960276 hasConceptScore W2000960276C2781018748 @default.
- W2000960276 hasConceptScore W2000960276C2908646376 @default.
- W2000960276 hasConceptScore W2000960276C42219234 @default.
- W2000960276 hasConceptScore W2000960276C71924100 @default.
- W2000960276 hasIssue "1" @default.
- W2000960276 hasLocation W20009602761 @default.
- W2000960276 hasLocation W20009602762 @default.
- W2000960276 hasOpenAccess W2000960276 @default.
- W2000960276 hasPrimaryLocation W20009602761 @default.
- W2000960276 hasRelatedWork W2000960276 @default.
- W2000960276 hasRelatedWork W2109469343 @default.
- W2000960276 hasRelatedWork W2116148510 @default.
- W2000960276 hasRelatedWork W2116730534 @default.
- W2000960276 hasRelatedWork W2117546435 @default.
- W2000960276 hasRelatedWork W2161345955 @default.
- W2000960276 hasRelatedWork W2254606917 @default.
- W2000960276 hasRelatedWork W2409018592 @default.
- W2000960276 hasRelatedWork W2467907059 @default.
- W2000960276 hasRelatedWork W99239007 @default.
- W2000960276 hasVolume "138" @default.
- W2000960276 isParatext "false" @default.
- W2000960276 isRetracted "false" @default.
- W2000960276 magId "2000960276" @default.
- W2000960276 workType "article" @default.