Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000960776> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2000960776 endingPage "72" @default.
- W2000960776 startingPage "67" @default.
- W2000960776 abstract "Although the large use of diethylcarbamazine (DEC), as the major anti-filaricide drug, its mechanism of action remains a matter of controversy. Several authors defend the hypothesis that DEC has no direct effect on nematodes. This study demonstrated that infective larvae (L3) of Wuchereria bancrofti treated in vitro with DEC presented several behaviour and morphological changes. The first alteration produced by treatment for 2 h with 3, 5, 10 μg/ml of DEC was the reduction of motility. Larvae treated with 5, 10 μg/ml DEC showed severely affected organelles, formation of several vacuoles, mainly in neurocytes and in the muscle cells, and dissolution of cytoplasm. Some larvae showed extreme cellular disorganization with abundance of large and dense mitochondria and numerous large vacuoles containing residual organelles. Lamellar bodies, probably related to an assembly of hipodermal membranes, were also observed in some damaged larvae. Thus, undoubtedly in vitro treatment with concentrations of DEC similar to therapeutic conditions, which are 1–5 μg/ml (Hawking, 1979), had a direct effect on infective larvae of W. bancrofti by causing, primarily neuromuscular alterations with subsequent damage to organelles." @default.
- W2000960776 created "2016-06-24" @default.
- W2000960776 creator A5001629093 @default.
- W2000960776 creator A5008146061 @default.
- W2000960776 creator A5021835234 @default.
- W2000960776 creator A5089434421 @default.
- W2000960776 date "2005-01-01" @default.
- W2000960776 modified "2023-09-26" @default.
- W2000960776 title "The ultrastructure of infective larvae (L3) of Wuchereria bancrofti after treatment with diethylcarbamazine" @default.
- W2000960776 cites W1036773581 @default.
- W2000960776 cites W1966495800 @default.
- W2000960776 cites W2004175779 @default.
- W2000960776 cites W2016373381 @default.
- W2000960776 cites W2041380452 @default.
- W2000960776 cites W2053472151 @default.
- W2000960776 cites W2055748951 @default.
- W2000960776 cites W2086325777 @default.
- W2000960776 cites W2126749862 @default.
- W2000960776 cites W2142600941 @default.
- W2000960776 cites W2315802110 @default.
- W2000960776 cites W2399754173 @default.
- W2000960776 cites W4298159997 @default.
- W2000960776 cites W4301520287 @default.
- W2000960776 doi "https://doi.org/10.1016/j.micron.2004.05.003" @default.
- W2000960776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15582480" @default.
- W2000960776 hasPublicationYear "2005" @default.
- W2000960776 type Work @default.
- W2000960776 sameAs 2000960776 @default.
- W2000960776 citedByCount "12" @default.
- W2000960776 countsByYear W20009607762012 @default.
- W2000960776 countsByYear W20009607762016 @default.
- W2000960776 countsByYear W20009607762019 @default.
- W2000960776 crossrefType "journal-article" @default.
- W2000960776 hasAuthorship W2000960776A5001629093 @default.
- W2000960776 hasAuthorship W2000960776A5008146061 @default.
- W2000960776 hasAuthorship W2000960776A5021835234 @default.
- W2000960776 hasAuthorship W2000960776A5089434421 @default.
- W2000960776 hasConcept C102568950 @default.
- W2000960776 hasConcept C105702510 @default.
- W2000960776 hasConcept C136764020 @default.
- W2000960776 hasConcept C165901193 @default.
- W2000960776 hasConcept C168240541 @default.
- W2000960776 hasConcept C173758957 @default.
- W2000960776 hasConcept C190062978 @default.
- W2000960776 hasConcept C202751555 @default.
- W2000960776 hasConcept C203014093 @default.
- W2000960776 hasConcept C2777411658 @default.
- W2000960776 hasConcept C2777629521 @default.
- W2000960776 hasConcept C2778672586 @default.
- W2000960776 hasConcept C41008148 @default.
- W2000960776 hasConcept C55493867 @default.
- W2000960776 hasConcept C59822182 @default.
- W2000960776 hasConcept C71928629 @default.
- W2000960776 hasConcept C86803240 @default.
- W2000960776 hasConcept C87555872 @default.
- W2000960776 hasConcept C89423630 @default.
- W2000960776 hasConcept C95444343 @default.
- W2000960776 hasConceptScore W2000960776C102568950 @default.
- W2000960776 hasConceptScore W2000960776C105702510 @default.
- W2000960776 hasConceptScore W2000960776C136764020 @default.
- W2000960776 hasConceptScore W2000960776C165901193 @default.
- W2000960776 hasConceptScore W2000960776C168240541 @default.
- W2000960776 hasConceptScore W2000960776C173758957 @default.
- W2000960776 hasConceptScore W2000960776C190062978 @default.
- W2000960776 hasConceptScore W2000960776C202751555 @default.
- W2000960776 hasConceptScore W2000960776C203014093 @default.
- W2000960776 hasConceptScore W2000960776C2777411658 @default.
- W2000960776 hasConceptScore W2000960776C2777629521 @default.
- W2000960776 hasConceptScore W2000960776C2778672586 @default.
- W2000960776 hasConceptScore W2000960776C41008148 @default.
- W2000960776 hasConceptScore W2000960776C55493867 @default.
- W2000960776 hasConceptScore W2000960776C59822182 @default.
- W2000960776 hasConceptScore W2000960776C71928629 @default.
- W2000960776 hasConceptScore W2000960776C86803240 @default.
- W2000960776 hasConceptScore W2000960776C87555872 @default.
- W2000960776 hasConceptScore W2000960776C89423630 @default.
- W2000960776 hasConceptScore W2000960776C95444343 @default.
- W2000960776 hasIssue "1" @default.
- W2000960776 hasLocation W20009607761 @default.
- W2000960776 hasLocation W20009607762 @default.
- W2000960776 hasOpenAccess W2000960776 @default.
- W2000960776 hasPrimaryLocation W20009607761 @default.
- W2000960776 hasRelatedWork W2000960776 @default.
- W2000960776 hasRelatedWork W2007730257 @default.
- W2000960776 hasRelatedWork W2020849778 @default.
- W2000960776 hasRelatedWork W2053472151 @default.
- W2000960776 hasRelatedWork W2142600941 @default.
- W2000960776 hasRelatedWork W2314515615 @default.
- W2000960776 hasRelatedWork W2373132375 @default.
- W2000960776 hasRelatedWork W2403675891 @default.
- W2000960776 hasRelatedWork W2413665020 @default.
- W2000960776 hasRelatedWork W2423772214 @default.
- W2000960776 hasVolume "36" @default.
- W2000960776 isParatext "false" @default.
- W2000960776 isRetracted "false" @default.
- W2000960776 magId "2000960776" @default.
- W2000960776 workType "article" @default.