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- W2000962328 abstract "Abstract Dose-effect relationships for apomorphine and amphetamine on lever-pressing behavior of rats, maintained by a 2 min fixed-interval schedule of water presentation, were determined. Lower doses of amphetamine increased responding particularly when control base-line rates were low, whereas higher doses decreased responding. In contrast, doses of apomorphine only decreased responding. Chronic reserpine treatment reduced the base-line response rate to approximately 15% of the mean control rate. Certain doses of amphetamine, but not apomorphine, partially antagonized the rate-depressant effect of reserpine. Since apomorphine stimulates central dopamine receptors, the present results suggest that dopaminergic mechanisms are not significantly involved in the mediation of the rate stimulant effects of amphetamine on operant behavior." @default.
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- W2000962328 date "1972-05-01" @default.
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- W2000962328 title "Comparison between the effects of apomorphine and amphetamine on operant behavior" @default.
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- W2000962328 doi "https://doi.org/10.1016/0014-2999(72)90237-3" @default.
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