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- W2000963174 abstract "Lychnophora salicifolia, commonly known as arnicão, is used as an anti-inflammatory agent and as a flavoring agent in the Brazilian traditional spirit cachaça. In this work, the permeation process of vicenin-2 (1) and lychnopholic acid (2) (major secondary metabolites from the hydroalcoholic extract) was investigated using Caco-2 cells. For this investigation, a new HPLC-DAD method was developed and validated for the quantification step. It was observed that 2 crosses the Caco-2 cell monolayer by passive diffusion. On the other hand, 1 was not transported, suggesting no absorption and no efflux of this compound in Caco-2 cells." @default.
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- W2000963174 date "2013-11-26" @default.
- W2000963174 modified "2023-10-06" @default.
- W2000963174 title "Evaluation of Intestinal Permeability of Vicenin-2 and Lychnopholic Acid from <i>Lychnophora salicifolia</i> (Brazilian Arnicão) Using Caco-2 Cells" @default.
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- W2000963174 doi "https://doi.org/10.1021/np400674t" @default.
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