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• W2000972886 abstract "Maternal cardiac disease is among the most significant causes of nonobstetric mortality during pregnancy. Mitral stenosis (MS) is the most frequent valvular disease in women of childbearing age. We reviewed our experience of 636 cases of cardiac disease during pregnancy out of which 363 had rheumatic heart disease and 151 had MS. Forty pts with MS undervvent an intervention during pregnancy due to cardiac failure (36 pts) or hemoptysis (4 pts). Open comissurotomy with high flow and without hypothermia was performed in 24 pts in the last thirteen years, gestational age varying from 4 to 30 weeks, anoxia from 7 to 28 minutes and perfusion time from 12 to 41 minutes. One woman and her fetus died due to coagulopathy in the intraoperative period; no further maternal morbidity occurred but there were 4 other fetal deaths in the immediate postoperative period, prematurity was 40% and small for gestational age 13.3% in 15 newborns delivered at our hospital. Sixteen pts undervvent mitral balloon valvuloplasty (MBV) in the last three years, gestalional age varying from 5 to 34 weeks with an average Block score of 7. All of them improved the mitral valve area by more than 50%, mean area by echo-Doppler increasing from 0.9 to 1.8 cm 2 with the mean left atrium-LV gradient falling from 19.0 to 5.0 mmHg. Mitral in Sufficiency was rated as ++/++++ in 2 pts and pericardial perforation occurred in 3 pts without tamponade. Maternal mortality was 0% and no pt had to go to surgery during pregnancy but there was 1 fetal death (6.2%); one premature and one baby small for gestational age occurred in the other 15 deliveries. MBV compares favourably against open comissurotomy in pregnant women with MS concerning: maternal death (0.0% × 4.1%), fetal death (6.2% × 20.8%—P < 0.05). prematurity (6.2% × 40.0%—P < 0.05) and small for gestational age (6.2% × 13.3%). MBV is now the procedure of choice at our institution for pts with MS that require an intervention during pregnancy." @default.
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• W2000972886 date "1995-02-01" @default.
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• W2000972886 title "1024-80 Mitral Stenosis and Pregnancy: Balloon Valvuloplasty Against Open Comissurotomy" @default.
• W2000972886 doi "https://doi.org/10.1016/0735-1097(95)93133-w" @default.
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