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- W2000974245 abstract "Respiratory chemoreceptors are neurons that detect PCO(2), PO(2), and/or pH in body fluids and provide sensory feedback for the control of breathing. They play a critical role in coupling pulmonary ventilation to metabolic demand in endothermic vertebrates. During birth in mammals and hatching in birds, the state change from placental or chorioallantoic gas exchange to pulmonary respiration makes acute demands on the neonatal lungs and ventilatory control system, including the respiratory chemoreceptors. Here we review the literature on prenatal development of carotid body chemoreceptors, central chemoreceptors, and airway chemoreceptors, with emphasis on the histology, histochemistry, and neurophysiology of chemosensory cells or their afferents, and their physiological genomics if known. In general, respiratory chemoreceptors develop prenatally and are functional but immature at birth or hatching. Each type of respiratory chemoreceptor has a unique prenatal developmental time course, and all studied to date require a period of postnatal maturation to express the full adult response." @default.
- W2000974245 created "2016-06-24" @default.
- W2000974245 creator A5033319774 @default.
- W2000974245 creator A5038588762 @default.
- W2000974245 date "2011-08-01" @default.
- W2000974245 modified "2023-09-24" @default.
- W2000974245 title "Prenatal development of respiratory chemoreceptors in endothermic vertebrates" @default.
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- W2000974245 doi "https://doi.org/10.1016/j.resp.2011.04.027" @default.
- W2000974245 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3146631" @default.
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