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- W2000978693 abstract "Biofilm formation is an important step in the etiology of periodontal diseases. In this study, in vitro biofilm formation by Treponema denticola and Porphyromonas gingivalis 381 displayed synergistic effects. Confocal microscopy demonstrated that P. gingivalis attaches to the substratum first as a primary colonizer followed by coaggregation with T. denticola to form a mixed biofilm. The T. denticola flagella mutant as well as the cytoplasmic filament mutant were shown to be essential for biofilm formation as well as coaggregation with P. gingivalis. The major fimbriae and Arg-gingipain B of P. gingivalis also play important roles in biofilm formation with T. denticola." @default.
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- W2000978693 date "2005-09-01" @default.
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- W2000978693 title "Synergistic biofilm formation by<i>Treponema denticola</i>and<i>Porphyromonas gingivalis</i>" @default.
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- W2000978693 doi "https://doi.org/10.1016/j.femsle.2005.07.019" @default.
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