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- W2000985909 abstract "Objectives:1) Describe factors associated with development, disease control, and rate of recurrence in patients with Idiopathic Subglottic Stenosis (ISS). 2) Evaluate the relationship between Body Mass Index (BMI) and ISS. Methods:A retrospective chart review was performed for patients treated at the Mayo Clinic Rochester between 1996 and December 2012. All patients 16 years and older with a clinical diagnosis and/or treatment of ISS were reviewed. Patients with an identifiable etiology for stenosis including trauma, prior neck surgery, previous tracheostomy, multiple intubations (>6 lifetime intubations), prolonged intubation (>1 week), Wegener’s Granulomatosis, or an antecedent explanation for their stenosis were excluded. Outcome measurements included symptom free interval, recurrence, and number of procedures performed. Results:Features were collected on 182 female and 4 male patients. At diagnosis, 121 (65%) patients were overweight, and 76 (41%) patients were obese. The mean BMI at first surgery was 28.7 kg/m2. Ninety-one patients experienced at least one recurrence at a mean of 2.3 years following treatment. Mean number of recurrences, relative to follow-up interval, for class BMI >30.0 kg/m2 was 1.6 recurrences/year compared with 1.0 recurrences/year for BMI < 30 kg/m2 (P = 0.050). Increasing incidence of the following comorbidities was significantly associated with increases in BMI: heartburn (P = 0.012), gastroesophageal reflux disease (P = 0.011), hypertension (P = <0.001), cardiac history (P = 0.045), hyperlipidemia/dyslipidemia (P = <0.001), and diabetes mellitus (P = 0.004). Conclusions:ISS patients with elevated BMI appear to have an increased risk of recurrent disease. Encouraging lifestyle change and weight reduction may assist in disease control." @default.
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- W2000985909 date "2013-08-23" @default.
- W2000985909 modified "2023-09-26" @default.
- W2000985909 title "Association of Idiopathic Subglottic Stenosis and Body Mass Index" @default.
- W2000985909 doi "https://doi.org/10.1177/0194599813496044a183" @default.
- W2000985909 hasPublicationYear "2013" @default.
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