Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000987296> ?p ?o ?g. }
- W2000987296 endingPage "211" @default.
- W2000987296 startingPage "199" @default.
- W2000987296 abstract "It is assumed that stress-related changes in the endocrine and immune systems are key mediators involved in the development of diseases associated with posttraumatic stress disorder (PTSD). Evidence suggests that those changes might be related to the duration of PTSD. The aim of our study was to investigate the differences in selected endocrine- and immune-related variables between PTSD patients and control subjects, and whether these differences persist over time.We assessed 39 Croatian war veterans with PTSD and 25 healthy volunteers (civilians without traumatic experience), all men, at two time points separated by 5.6 years (median; interquartile range: 5.4-6.3). Cortisol and prolactin levels were measured by radioimmunoassays while interleukin-6 and tumor necrosis factor-α were determined by enzyme-linked immunosorbent assays. Immune function was assessed by in vitro natural killer cell cytotoxicity (NKCC). Lymphocyte counts, immunophenotype and intracellular glucocorticoid receptor expression in various lymphocyte subsets were determined by three-color flow cytometry.At the first assessment, moderate to large effect size estimates of differences between patients and controls were observed for most of the measured variables. Only prolactin levels and lymphocyte counts remained significantly elevated in PTSD patients at the second assessment with low to moderate effect size estimates of differences between patients and controls in other variables.Observed endocrine- and immune-related changes in PTSD over time may depend on the duration of the allostatic load posed by the disorder and its impact on interactions between the endocrine and immune systems involved in stress response." @default.
- W2000987296 created "2016-06-24" @default.
- W2000987296 creator A5009909871 @default.
- W2000987296 creator A5016572077 @default.
- W2000987296 creator A5023293805 @default.
- W2000987296 creator A5024216636 @default.
- W2000987296 creator A5030179373 @default.
- W2000987296 creator A5040144637 @default.
- W2000987296 creator A5040455380 @default.
- W2000987296 creator A5044613607 @default.
- W2000987296 date "2011-01-01" @default.
- W2000987296 modified "2023-10-15" @default.
- W2000987296 title "Repeated Assessments of Endocrine- and Immune-Related Changes in Posttraumatic Stress Disorder" @default.
- W2000987296 cites W104224639 @default.
- W2000987296 cites W141444043 @default.
- W2000987296 cites W1887562084 @default.
- W2000987296 cites W1964078902 @default.
- W2000987296 cites W1964847710 @default.
- W2000987296 cites W1966623608 @default.
- W2000987296 cites W1969298809 @default.
- W2000987296 cites W1971951429 @default.
- W2000987296 cites W1972518602 @default.
- W2000987296 cites W1974077278 @default.
- W2000987296 cites W1974331611 @default.
- W2000987296 cites W1975914687 @default.
- W2000987296 cites W1978208774 @default.
- W2000987296 cites W1981277472 @default.
- W2000987296 cites W1982045506 @default.
- W2000987296 cites W1982301384 @default.
- W2000987296 cites W1982900958 @default.
- W2000987296 cites W1986944693 @default.
- W2000987296 cites W1989618975 @default.
- W2000987296 cites W1990361157 @default.
- W2000987296 cites W1990652217 @default.
- W2000987296 cites W1991903108 @default.
- W2000987296 cites W1994387933 @default.
- W2000987296 cites W1997741731 @default.
- W2000987296 cites W2003011144 @default.
- W2000987296 cites W2008967635 @default.
- W2000987296 cites W2009545719 @default.
- W2000987296 cites W2009737522 @default.
- W2000987296 cites W2014520755 @default.
- W2000987296 cites W2021835371 @default.
- W2000987296 cites W2024416743 @default.
- W2000987296 cites W2025434317 @default.
- W2000987296 cites W2027845679 @default.
- W2000987296 cites W2031575606 @default.
- W2000987296 cites W2031646626 @default.
- W2000987296 cites W2033049627 @default.
- W2000987296 cites W2039297066 @default.
- W2000987296 cites W2040975346 @default.
- W2000987296 cites W2044677703 @default.
- W2000987296 cites W2049124236 @default.
- W2000987296 cites W2050802204 @default.
- W2000987296 cites W2052959069 @default.
- W2000987296 cites W2053181767 @default.
- W2000987296 cites W2058660680 @default.
- W2000987296 cites W2062438314 @default.
- W2000987296 cites W2063694580 @default.
- W2000987296 cites W2066563259 @default.
- W2000987296 cites W2069336217 @default.
- W2000987296 cites W2070362655 @default.
- W2000987296 cites W2071057820 @default.
- W2000987296 cites W2071404781 @default.
- W2000987296 cites W2073376147 @default.
- W2000987296 cites W2073383921 @default.
- W2000987296 cites W2077017047 @default.
- W2000987296 cites W2077326058 @default.
- W2000987296 cites W2079243187 @default.
- W2000987296 cites W2080377366 @default.
- W2000987296 cites W2081865906 @default.
- W2000987296 cites W2082574777 @default.
- W2000987296 cites W2091312722 @default.
- W2000987296 cites W2093982682 @default.
- W2000987296 cites W2094448304 @default.
- W2000987296 cites W2103141792 @default.
- W2000987296 cites W2107337543 @default.
- W2000987296 cites W2108617039 @default.
- W2000987296 cites W2110065044 @default.
- W2000987296 cites W2115742753 @default.
- W2000987296 cites W2118210398 @default.
- W2000987296 cites W2137219871 @default.
- W2000987296 cites W2137959792 @default.
- W2000987296 cites W2139825658 @default.
- W2000987296 cites W2147666979 @default.
- W2000987296 cites W2149366513 @default.
- W2000987296 cites W2149965808 @default.
- W2000987296 cites W2151002840 @default.
- W2000987296 cites W2159184393 @default.
- W2000987296 cites W2160186948 @default.
- W2000987296 cites W2163143776 @default.
- W2000987296 cites W2171512984 @default.
- W2000987296 cites W2487041115 @default.
- W2000987296 cites W2491207572 @default.
- W2000987296 cites W2793833913 @default.
- W2000987296 cites W3090293687 @default.
- W2000987296 cites W49144085 @default.
- W2000987296 doi "https://doi.org/10.1159/000322869" @default.