FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000987712> ?p ?o ?g. }

• W2000987712 endingPage "258" @default.
• W2000987712 startingPage "252" @default.
• W2000987712 abstract "Virus-specific cytotoxic T lymphocytes (CTLs) in the lung are considered to confer protection from respiratory viruses. Several groups demonstrated that the route of priming was likely to have an implication for the trafficking of antigen-specific CTLs. Therefore, we investigated whether the route of immunization with adenoviral vaccine influenced the recruitment of virus-specific CTLs in the lung that should provide potent protection from influenza A virus. Mice were immunized with recombinant adenovirus expressing the matrix (M1) protein of influenza A virus via various immunization routes involving intraperitoneal, intranasal, intramuscular, or intravenous administration as well as subcutaneous administration in the hind hock. We found that the immunization route dramatically impacted the recruitment of M1-specific IFN-γ+ CD8+ T cells both in the lung and the spleen. Surprisingly, hock immunization was most effective for the accumulation in the lung of IFN-γ-producing CD8+ T cells that possessed M1-specific cytolytic activity. Further, antigen-driven IFN-γ+ CD8+ T cells in the lung, but not in the spleen, were likely to be correlated with the resistance to challenge with influenza A virus. These results may improve our ability to design vaccines that target virus-specific CTL responses to respiratory viruses such as influenza A virus." @default.
• W2000987712 created "2016-06-24" @default.
• W2000987712 creator A5027857045 @default.
• W2000987712 creator A5051628580 @default.
• W2000987712 creator A5052670145 @default.
• W2000987712 creator A5060130752 @default.
• W2000987712 creator A5065160596 @default.
• W2000987712 creator A5089351102 @default.
• W2000987712 date "2011-09-01" @default.
• W2000987712 modified "2023-09-25" @default.
• W2000987712 title "The route of immunization with adenoviral vaccine influences the recruitment of cytotoxic T lymphocytes in the lung that provide potent protection from influenza A virus" @default.
• W2000987712 cites W1601917502 @default.
• W2000987712 cites W1925250285 @default.
• W2000987712 cites W1964282322 @default.
• W2000987712 cites W1967176093 @default.
• W2000987712 cites W1967684158 @default.
• W2000987712 cites W1967927764 @default.
• W2000987712 cites W1968439321 @default.
• W2000987712 cites W1975524894 @default.
• W2000987712 cites W2009165647 @default.
• W2000987712 cites W2011238385 @default.
• W2000987712 cites W2039800389 @default.
• W2000987712 cites W2052899203 @default.
• W2000987712 cites W2063929734 @default.
• W2000987712 cites W2079734745 @default.
• W2000987712 cites W2099926545 @default.
• W2000987712 cites W2121572966 @default.
• W2000987712 cites W2127532535 @default.
• W2000987712 cites W2134351140 @default.
• W2000987712 cites W2134777801 @default.
• W2000987712 cites W2138205821 @default.
• W2000987712 cites W2141211088 @default.
• W2000987712 cites W2141304440 @default.
• W2000987712 cites W2150014596 @default.
• W2000987712 cites W2155104070 @default.
• W2000987712 cites W2169447203 @default.
• W2000987712 cites W4211240312 @default.
• W2000987712 doi "https://doi.org/10.1016/j.antiviral.2011.06.008" @default.
• W2000987712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21722671" @default.
• W2000987712 hasPublicationYear "2011" @default.
• W2000987712 type Work @default.
• W2000987712 sameAs 2000987712 @default.
• W2000987712 citedByCount "17" @default.
• W2000987712 countsByYear W20009877122012 @default.
• W2000987712 countsByYear W20009877122013 @default.
• W2000987712 countsByYear W20009877122014 @default.
• W2000987712 countsByYear W20009877122015 @default.
• W2000987712 countsByYear W20009877122016 @default.
• W2000987712 countsByYear W20009877122017 @default.
• W2000987712 crossrefType "journal-article" @default.
• W2000987712 hasAuthorship W2000987712A5027857045 @default.
• W2000987712 hasAuthorship W2000987712A5051628580 @default.
• W2000987712 hasAuthorship W2000987712A5052670145 @default.
• W2000987712 hasAuthorship W2000987712A5060130752 @default.
• W2000987712 hasAuthorship W2000987712A5065160596 @default.
• W2000987712 hasAuthorship W2000987712A5089351102 @default.
• W2000987712 hasConcept C147483822 @default.
• W2000987712 hasConcept C147969180 @default.
• W2000987712 hasConcept C154317977 @default.
• W2000987712 hasConcept C159047783 @default.
• W2000987712 hasConcept C167672396 @default.
• W2000987712 hasConcept C202751555 @default.
• W2000987712 hasConcept C203014093 @default.
• W2000987712 hasConcept C2522874641 @default.
• W2000987712 hasConcept C2777546802 @default.
• W2000987712 hasConcept C2780801004 @default.
• W2000987712 hasConcept C55493867 @default.
• W2000987712 hasConcept C71924100 @default.
• W2000987712 hasConcept C86803240 @default.
• W2000987712 hasConceptScore W2000987712C147483822 @default.
• W2000987712 hasConceptScore W2000987712C147969180 @default.
• W2000987712 hasConceptScore W2000987712C154317977 @default.
• W2000987712 hasConceptScore W2000987712C159047783 @default.
• W2000987712 hasConceptScore W2000987712C167672396 @default.
• W2000987712 hasConceptScore W2000987712C202751555 @default.
• W2000987712 hasConceptScore W2000987712C203014093 @default.
• W2000987712 hasConceptScore W2000987712C2522874641 @default.
• W2000987712 hasConceptScore W2000987712C2777546802 @default.
• W2000987712 hasConceptScore W2000987712C2780801004 @default.
• W2000987712 hasConceptScore W2000987712C55493867 @default.
• W2000987712 hasConceptScore W2000987712C71924100 @default.
• W2000987712 hasConceptScore W2000987712C86803240 @default.
• W2000987712 hasIssue "3" @default.
• W2000987712 hasLocation W20009877121 @default.
• W2000987712 hasLocation W20009877122 @default.
• W2000987712 hasOpenAccess W2000987712 @default.
• W2000987712 hasPrimaryLocation W20009877121 @default.
• W2000987712 hasRelatedWork W1506455075 @default.
• W2000987712 hasRelatedWork W1551043459 @default.
• W2000987712 hasRelatedWork W1964955632 @default.
• W2000987712 hasRelatedWork W1979511395 @default.
• W2000987712 hasRelatedWork W1980416103 @default.
• W2000987712 hasRelatedWork W2018916009 @default.
• W2000987712 hasRelatedWork W2052483994 @default.
• W2000987712 hasRelatedWork W2053177727 @default.
• W2000987712 hasRelatedWork W2054101033 @default.
• W2000987712 hasRelatedWork W2076874973 @default.
• W2000987712 hasVolume "91" @default.

• next