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- W2000989481 abstract "A sensitive specific method is described for the determination of phenylbutazone in plasma. After simple solvent extraction from 1 ml of plasma the drug was estimated without interference from the known metabolites, oxyphenbutazone and the side-chain hydroxyphenylbutazone, by gas-liquid chromatography using a flame ionization detector. The procedure compared favourably with a less specific spectrophotometric method and was of sufficient sensitivity to determine plasma levels (<0.5 μg/ml) of the drug after single 200-mg doses." @default.
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- W2000989481 date "1974-02-01" @default.
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- W2000989481 title "The assay of phenylbutazone in human plasma by a specific and sensitive gas-liquid chromatographic procedure" @default.
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- W2000989481 doi "https://doi.org/10.1016/s0021-9673(01)84154-6" @default.
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