Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000993949> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2000993949 endingPage "407" @default.
- W2000993949 startingPage "399" @default.
- W2000993949 abstract "We have previously demonstrated that hypoxia is acutely epileptogenic in the immature rat but not in the adult. The window during which hypoxia induces seizures in the rat ranges from postnatal day (P) 5–17, with the most severe seizures occurring at P10–12. Perinatal hypoxia resulted in significantly more acute seizure activity than perinatal anoxia. The present study evaluates the long term effects of perinatal hypoxia versus anoxia. Animals were exposed to hypoxia (3%O2) or anoxia (0%O2) at P10 and challenged later in adulthood (P55–60) with administration of pentylenetetrazol (PTZ) (45 mg/kg subcutaneously). Compared to normal littermate controls, the animals which had been exposed to perinatal hypoxia had a significantly higher frequency of generalized convulsions (GC) and a significantly shorter latency to the first myoclonic jerk (MJ) after PTZ. In contrast, perinatal anoxia did not alter long term seizure susceptibility. These results are discussed in context of previous studies which have shown variable long term effects using different models of perinatal hypoxia and/or ischemia." @default.
- W2000993949 created "2016-06-24" @default.
- W2000993949 creator A5030606685 @default.
- W2000993949 creator A5033300783 @default.
- W2000993949 creator A5038568999 @default.
- W2000993949 creator A5061661577 @default.
- W2000993949 date "1991-01-01" @default.
- W2000993949 modified "2023-10-16" @default.
- W2000993949 title "Differential effects of perinatal hypoxia and anoxia on long term seizure susceptibility in the rat" @default.
- W2000993949 cites W1534709134 @default.
- W2000993949 cites W1979299616 @default.
- W2000993949 cites W2052514786 @default.
- W2000993949 cites W2054223832 @default.
- W2000993949 cites W2055316863 @default.
- W2000993949 cites W2060987956 @default.
- W2000993949 cites W2064960925 @default.
- W2000993949 cites W2095942484 @default.
- W2000993949 cites W2152475434 @default.
- W2000993949 cites W2171558421 @default.
- W2000993949 doi "https://doi.org/10.1016/0024-3205(91)90448-k" @default.
- W2000993949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1857188" @default.
- W2000993949 hasPublicationYear "1991" @default.
- W2000993949 type Work @default.
- W2000993949 sameAs 2000993949 @default.
- W2000993949 citedByCount "46" @default.
- W2000993949 countsByYear W20009939492012 @default.
- W2000993949 countsByYear W20009939492015 @default.
- W2000993949 countsByYear W20009939492017 @default.
- W2000993949 countsByYear W20009939492022 @default.
- W2000993949 crossrefType "journal-article" @default.
- W2000993949 hasAuthorship W2000993949A5030606685 @default.
- W2000993949 hasAuthorship W2000993949A5033300783 @default.
- W2000993949 hasAuthorship W2000993949A5038568999 @default.
- W2000993949 hasAuthorship W2000993949A5061661577 @default.
- W2000993949 hasConcept C118552586 @default.
- W2000993949 hasConcept C126322002 @default.
- W2000993949 hasConcept C134018914 @default.
- W2000993949 hasConcept C178790620 @default.
- W2000993949 hasConcept C185592680 @default.
- W2000993949 hasConcept C2775858608 @default.
- W2000993949 hasConcept C2776819090 @default.
- W2000993949 hasConcept C2778186239 @default.
- W2000993949 hasConcept C2779914510 @default.
- W2000993949 hasConcept C2780164069 @default.
- W2000993949 hasConcept C42219234 @default.
- W2000993949 hasConcept C540031477 @default.
- W2000993949 hasConcept C71924100 @default.
- W2000993949 hasConcept C7836513 @default.
- W2000993949 hasConceptScore W2000993949C118552586 @default.
- W2000993949 hasConceptScore W2000993949C126322002 @default.
- W2000993949 hasConceptScore W2000993949C134018914 @default.
- W2000993949 hasConceptScore W2000993949C178790620 @default.
- W2000993949 hasConceptScore W2000993949C185592680 @default.
- W2000993949 hasConceptScore W2000993949C2775858608 @default.
- W2000993949 hasConceptScore W2000993949C2776819090 @default.
- W2000993949 hasConceptScore W2000993949C2778186239 @default.
- W2000993949 hasConceptScore W2000993949C2779914510 @default.
- W2000993949 hasConceptScore W2000993949C2780164069 @default.
- W2000993949 hasConceptScore W2000993949C42219234 @default.
- W2000993949 hasConceptScore W2000993949C540031477 @default.
- W2000993949 hasConceptScore W2000993949C71924100 @default.
- W2000993949 hasConceptScore W2000993949C7836513 @default.
- W2000993949 hasIssue "5" @default.
- W2000993949 hasLocation W20009939491 @default.
- W2000993949 hasLocation W20009939492 @default.
- W2000993949 hasOpenAccess W2000993949 @default.
- W2000993949 hasPrimaryLocation W20009939491 @default.
- W2000993949 hasRelatedWork W198158046 @default.
- W2000993949 hasRelatedWork W1983627813 @default.
- W2000993949 hasRelatedWork W2012068506 @default.
- W2000993949 hasRelatedWork W2056878431 @default.
- W2000993949 hasRelatedWork W2139951348 @default.
- W2000993949 hasRelatedWork W2315057010 @default.
- W2000993949 hasRelatedWork W2359204949 @default.
- W2000993949 hasRelatedWork W2377865526 @default.
- W2000993949 hasRelatedWork W2385802693 @default.
- W2000993949 hasRelatedWork W3211198829 @default.
- W2000993949 hasVolume "49" @default.
- W2000993949 isParatext "false" @default.
- W2000993949 isRetracted "false" @default.
- W2000993949 magId "2000993949" @default.
- W2000993949 workType "article" @default.