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- W2000995787 abstract "The injection of 2 or 5 μg. of epinephrine into the coronary artery of anesthetized dogs produced an elevation in the S-T segment and a deepening of an already negative T wave in lead aVF. With a dose of 10 μg., the QRS complex became deformed, resembling the pattern of left bundle block. With these doses of epinephrine, the P wave was consistently affected, most frequently involving inversion with a shortening of the P-R interval. This finding suggested abnormal atrial activation attributable to a nodal or low left atrial rhythm. The administration of acetylcholine produced electrocardiographic changes similar to those seen following epinephrine injection, except that the P wave was unaffected. The similarity between the effects on the T wave, S-T segment, and QRS complex indicated that perhaps acetylcholine induced these changes through a release of myocardial catecholamines. The failure, however, to induce P wave changes is difficult to explain based on this interpretation." @default.
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- W2000995787 title "Acute effects of epinephrine and acetylcholine on the electrocardiogram of the dog" @default.
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- W2000995787 doi "https://doi.org/10.1016/0002-9149(66)90260-8" @default.
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