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- W2000997060 abstract "Avian <em>influenza</em> is a viral infection which affects mainly the respiratory system of birds. The H9N2 considered as low pathogenic avian <em>influenza</em> (LPAI) virus and continuously circulating in poultry flocks causing enormous economic losses to poultry industry of Pakistan. As these viruses have RNA genome and their RNA polymerase enzyme lacks proof reading activity which resulted in spontaneous mutation in surface glycoproteins (HA and NA) and reassortment of their genomic segments results in escape from host immune response produced by the vaccine. Efforts made for the isolation and identification of avian <em>influenza</em> virus from live desi and zoo birds of Lahore and performed antigenic characterization. The local vaccines although gives a little bit less titer when we raise the antisera against these vaccines but their antisera have more interaction with the local H9 subtype antigen so it gives better protective immune response. Infected chicken antisera are more reactive as compare to rabbit antisera. This shows that our isolates have highest similarity with the currently circulating viruses. These results guided us to devise a new control strategy against avian <em>influenza</em> viral infections. The antigenic characterization of these avian <em>influenza</em> isolates helped us to see the antigenic differences between the isolates of this study and H9 subtype avian influenza viruses used in vaccines. Therefore, this study clearly suggests that a new local H9 subtype avian <em>influenza</em> virus should be used as vaccinal candidate every year for the effective control of influenza viral infections of poultry." @default.
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- W2000997060 date "2011-08-31" @default.
- W2000997060 modified "2023-09-27" @default.
- W2000997060 title "Antigenic characterization of avian influenza H9 subtype isolated from desi and zoo birds" @default.
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- W2000997060 doi "https://doi.org/10.4081/mr.2011.e13" @default.
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