FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2001010012> ?p ?o ?g. }

• W2001010012 endingPage "25" @default.
• W2001010012 startingPage "18" @default.
• W2001010012 abstract "Active pharmaceutical ingredients (API) often crystallise in several forms with significant differences in their physical properties. In pharmaceutical applications it is very important to be able to identify these polymorphs during drug manufacturing and storaging, also quantitative information about polymorphs is often required. Solid state (13)C cross-polarisation (CP), magic angle spinning (MAS), nuclear magnetic resonance (NMR) spectroscopy was utilised in studying polymorphisity of an API with two polymorphic forms. Quantitative information was obtained from polymorphic mixtures, and a formulated product was also studied in order to determine the possibility of distinguishing between the two polymorphs in a low-dose formulation. Quantitative data was obtained using two methods: integration of signals from the dipolar dephased spectra, and a chemometric method known as Direct Exponential Curve Resolution Algorithm (DECRA). We concluded that the two polymorphs are easily identifiable based on their spectral differences. Quantitative results showed reasonable accuracy, and while identification of the polymorph present in formulation was not possible, traces of the API are detectable in as low dosage as 0.7% by weight using solid state NMR methods." @default.
• W2001010012 created "2016-06-24" @default.
• W2001010012 creator A5036393152 @default.
• W2001010012 creator A5062639795 @default.
• W2001010012 date "2010-07-01" @default.
• W2001010012 modified "2023-09-23" @default.
• W2001010012 title "Quantitation of a polymorphic mixture of an active pharmaceutical ingredient with solid state 13C CPMAS NMR spectroscopy" @default.
• W2001010012 cites W1542734677 @default.
• W2001010012 cites W1547487860 @default.
• W2001010012 cites W1967998310 @default.
• W2001010012 cites W1970797616 @default.
• W2001010012 cites W1973848482 @default.
• W2001010012 cites W1974409867 @default.
• W2001010012 cites W1980252947 @default.
• W2001010012 cites W1980913293 @default.
• W2001010012 cites W1999992136 @default.
• W2001010012 cites W2008252010 @default.
• W2001010012 cites W2008946186 @default.
• W2001010012 cites W2011285059 @default.
• W2001010012 cites W2024309761 @default.
• W2001010012 cites W2026934985 @default.
• W2001010012 cites W2031581087 @default.
• W2001010012 cites W2034056979 @default.
• W2001010012 cites W2035065700 @default.
• W2001010012 cites W2040004163 @default.
• W2001010012 cites W2052081265 @default.
• W2001010012 cites W2054130227 @default.
• W2001010012 cites W2054467935 @default.
• W2001010012 cites W2066387069 @default.
• W2001010012 cites W2068882246 @default.
• W2001010012 cites W2080909598 @default.
• W2001010012 cites W2133273904 @default.
• W2001010012 cites W2335875530 @default.
• W2001010012 cites W2951192655 @default.
• W2001010012 cites W317440518 @default.
• W2001010012 cites W8707387 @default.
• W2001010012 doi "https://doi.org/10.1016/j.ijpharm.2010.04.017" @default.
• W2001010012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20416365" @default.
• W2001010012 hasPublicationYear "2010" @default.
• W2001010012 type Work @default.
• W2001010012 sameAs 2001010012 @default.
• W2001010012 citedByCount "39" @default.
• W2001010012 countsByYear W20010100122012 @default.
• W2001010012 countsByYear W20010100122014 @default.
• W2001010012 countsByYear W20010100122015 @default.
• W2001010012 countsByYear W20010100122016 @default.
• W2001010012 countsByYear W20010100122017 @default.
• W2001010012 countsByYear W20010100122018 @default.
• W2001010012 countsByYear W20010100122019 @default.
• W2001010012 countsByYear W20010100122020 @default.
• W2001010012 countsByYear W20010100122021 @default.
• W2001010012 countsByYear W20010100122022 @default.
• W2001010012 countsByYear W20010100122023 @default.
• W2001010012 crossrefType "journal-article" @default.
• W2001010012 hasAuthorship W2001010012A5036393152 @default.
• W2001010012 hasAuthorship W2001010012A5062639795 @default.
• W2001010012 hasConcept C104317684 @default.
• W2001010012 hasConcept C106186310 @default.
• W2001010012 hasConcept C107814960 @default.
• W2001010012 hasConcept C113196181 @default.
• W2001010012 hasConcept C121332964 @default.
• W2001010012 hasConcept C1276947 @default.
• W2001010012 hasConcept C135763542 @default.
• W2001010012 hasConcept C147789679 @default.
• W2001010012 hasConcept C149737253 @default.
• W2001010012 hasConcept C153202636 @default.
• W2001010012 hasConcept C185592680 @default.
• W2001010012 hasConcept C192562407 @default.
• W2001010012 hasConcept C32891209 @default.
• W2001010012 hasConcept C43617362 @default.
• W2001010012 hasConcept C45904493 @default.
• W2001010012 hasConcept C46141821 @default.
• W2001010012 hasConcept C4839761 @default.
• W2001010012 hasConcept C55493867 @default.
• W2001010012 hasConcept C60644358 @default.
• W2001010012 hasConcept C62520636 @default.
• W2001010012 hasConcept C66974803 @default.
• W2001010012 hasConcept C67787023 @default.
• W2001010012 hasConcept C71240020 @default.
• W2001010012 hasConcept C77281830 @default.
• W2001010012 hasConcept C84935128 @default.
• W2001010012 hasConcept C86803240 @default.
• W2001010012 hasConceptScore W2001010012C104317684 @default.
• W2001010012 hasConceptScore W2001010012C106186310 @default.
• W2001010012 hasConceptScore W2001010012C107814960 @default.
• W2001010012 hasConceptScore W2001010012C113196181 @default.
• W2001010012 hasConceptScore W2001010012C121332964 @default.
• W2001010012 hasConceptScore W2001010012C1276947 @default.
• W2001010012 hasConceptScore W2001010012C135763542 @default.
• W2001010012 hasConceptScore W2001010012C147789679 @default.
• W2001010012 hasConceptScore W2001010012C149737253 @default.
• W2001010012 hasConceptScore W2001010012C153202636 @default.
• W2001010012 hasConceptScore W2001010012C185592680 @default.
• W2001010012 hasConceptScore W2001010012C192562407 @default.
• W2001010012 hasConceptScore W2001010012C32891209 @default.
• W2001010012 hasConceptScore W2001010012C43617362 @default.
• W2001010012 hasConceptScore W2001010012C45904493 @default.
• W2001010012 hasConceptScore W2001010012C46141821 @default.

• next