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- W2001031308 abstract "We describe a monoclonal antibody directed against a neuron-specific mitochondrial protein from rat brain. On protein blots the antibody recognizes a single polypeptide of apparent molecular weight of 23,000. By solid-phase immunoassay the antigen was detected in nonneural tissues. Within neurons, the antibody stains cytoplasmic granules that immunoelectron microscopy shows are mitochondria, hence the designation MIT-23. Immunocytochemical staining of the cerebellar cortex showed that MIT-23 occurs in all the neuronal types but is absent from glial and other nonneuronal cells. During neonatal development of the cerebellum, MIT-23 appears in neurons after their final cell division or migration is completed, suggesting that specific proteins associated with mitochondria participate in neuronal maturation." @default.
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- W2001031308 date "1982-02-01" @default.
- W2001031308 modified "2023-09-27" @default.
- W2001031308 title "MIT-23: A mitochondrial marker for terminal neuronal differentiation defined by a monoclonal antibody" @default.
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- W2001031308 doi "https://doi.org/10.1016/0092-8674(82)90343-9" @default.
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