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• W2001037013 abstract "A four-step synthesis of cis-3,5-disubstituted morpholines from enantiomerically pure amino alcohols is described. The key step in the synthesis is a Pd-catalyzed carboamination reaction between a substituted ethanolamine derivative and an aryl or alkenyl bromide. The morpholine products are generated as single stereoisomers in moderate to good yield. This strategy also provides access to fused bicyclic morpholines as well as 2,3- and 2,5-disubstituted products." @default.
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• W2001037013 date "2009-06-01" @default.
• W2001037013 modified "2023-10-13" @default.
• W2001037013 title "New Strategy for the Synthesis of Substituted Morpholines" @default.
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• W2001037013 doi "https://doi.org/10.1021/jo9007223" @default.
• W2001037013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2709957" @default.
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