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• W2001058545 abstract "A defective antioxidant scavenging system plays a major role in one of the theories of the pathogenesis of Parkinson9s disease. The aim of this study was to investigate whether there is a general difference in antioxidant activity between early and advanced cases of Parkinson9s disease. Twenty five recently diagnosed patients, without any clinical fluctuations (group A), and 25 patients in a late phase of the disease with severe fluctuations in response to levodopa therapy (group B) were included in the study. Erythrocyte glutathione peroxidase was determined as a measure of antioxidant activity and significantly lower values were found in group B than in group A. Regression analyses in groups A and B showed significant correlation between glutathione peroxidase and duration of disease, but not between glutathione peroxidase and age of patients." @default.
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• W2001058545 date "1991-08-01" @default.
• W2001058545 modified "2023-10-15" @default.
• W2001058545 title "Glutathione peroxidase in early and advanced Parkinson's disease." @default.
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• W2001058545 doi "https://doi.org/10.1136/jnnp.54.8.679" @default.
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